Electrodeposition of Au nanoparticles on poly(diallyldimethylammonium chloride) functionalized reduced graphene oxide sheets for voltammetric determination of nicotine in tobacco products and anti-smoking pharmaceuticals

Jing, Yanqiu; Lin, Erge; Su, Xinhong; Liu, Yingjie; Li, Huaiqi; Yuan, Xiuxiu; Lü, Ping; Yikuan, Fan

doi:10.1039/c6ra03399g

Cited by 14 publications

(2 citation statements)

References 56 publications

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“…After rinsing that modified electrode above, 20 μL of 1 μM probe RNA was introduced for 2 h incubation at 37 °C, and then it was rinsed to obtain the PEC biosensor. Synthesis of depositing Au NPs directly on the surface of ZnSe-COOH NFs was according to the reported method . The other related experimental procedures for the modification of the electrode were as same as the above process.…”

Section: Methodsmentioning

confidence: 99%

Dual Signal Amplification Using Gold Nanoparticles-Enhanced Zinc Selenide Nanoflakes and P19 Protein for Ultrasensitive Photoelectrochemical Biosensing of MicroRNA in Cell

Cao

Zhang

et al. 2016

Anal. Chem.

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Using Au nanoparticles (NPs)-decorated, water-soluble, ZnSe-COOH nanoflakes (NFs), an ultrasensitive photoelectrochemical (PEC) biosensing strategy based on the dual signal amplification was proposed. As a result of the localized surface plasmon resonance (SPR) of Au NPs, the ultraviolet-visible absorption spectrum of Au NPs overlapped with emission spectrum of ZnSe-COOH NFs, which generated efficient resonant energy transfer (RET) between ZnSe-COOH NFs and Au NPs. The RET improved photoelectric conversion efficiency of ZnSe-COOH NFs and significantly amplified PEC signal. Taking advantage of the specificity and high affinity of p19 protein for 21-23 bp double-stranded RNA, p19 protein was introduced. P19 protein could generate remarkable steric hindrance, which blocked interfacial electron transfer and impeded the access of the ascorbic acid to electrode surface for scavenging holes. This led to the dramatic decrease of photocurrent intensity and the amplification of PEC signal change versus concentration change of target. Using microRNA (miRNA)-122a as a model analyte, an ultrasensitive signal-off PEC biosensor for miRNA detection was developed under 405 nm irradiation at -0.30 V. Owing to RET and remarkable steric hindrance of p19 protein as dual signal amplification, the proposed strategy exhibited a wide linear range from 350 fM to 5 nM, with a low detection limit of 153 fM. It has been successfully applied to analyze the level of miRNA-122a in HeLa cell, which would have promising prospects for early diagnosis of tumor.

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Section: Methodsmentioning

confidence: 99%

Dual Signal Amplification Using Gold Nanoparticles-Enhanced Zinc Selenide Nanoflakes and P19 Protein for Ultrasensitive Photoelectrochemical Biosensing of MicroRNA in Cell

Cao

Zhang

et al. 2016

Anal. Chem.

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“…Figure 4 shows the site of absorption bands of functional groups in GO. The ex of broad stretching peaks at 3409 cm −1 , 2925 cm −1 , and 2857 cm −1 are stretching asym and symmetric a hydroxyl (O-H) and C-H groups of GO matrix [38][39][40]45], respe Moreover, the C=O stretching peak of the carboxylic (COOH) group at 1724 cm −1 , s ing band at 1626 cm −1 of aromatic C=C matrix of GO, and phenolic C-O mation,stretching, and epoxy C-O-C stretching were recognized at 1387, 1224 an cm −1 , respectively [38][39][40]46,47]. FT-IR spectroscopy is vital for describing functional moieties involved on GO's surface.…”

Section: Characterization Of the Synthesized Gomentioning

confidence: 99%

A Novel Electrochemical Sensor for Detection of Nicotine in Tobacco Products Based on Graphene Oxide Nanosheets Conjugated with (1,2-Naphthoquinone-4-Sulphonic Acid) Modified Glassy Carbon Electrode

et al. 2022

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A simple electrochemical sensor for nicotine (NIC) detection was performed. The sensor based on a glassy carbon electrode (GCE) was modified by (1,2-naphthoquinone-4-sulphonic acid)(Nq) decorated by graphene oxide (GO) nanocomposite. The synthesized (GO) nanosheets were characterized using X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscope (SEM), transmission electron microscope (TEM), FT-IR, and UV-Visible Spectroscopy. The insertion of Nq with GO nanosheets on the surface of GCE displayed high electrocatalytic activity towards NIC compared to the bare GCE. NIC determination was performed under the optimum conditions using 0.10 M of Na2SO4 as a supporting electrolyte with pH 8.0 at a scan rate of 100 mV/s using both cyclic voltammetry (CV) and differential pulse voltammetry (DPV). This electrochemical sensor showed an excellent result for NIC detection. The oxidation peak current increased linearly with a 6.5–245 µM of NIC with R2 = 0.9999. The limit of detection was 12.7 nM. The fabricated electrode provided satisfactory stability, reproducibility, and selectivity for NIC oxidation. The reliable GO/Nq/GCE sensor was successfully applied for detecting NIC in the tobacco product and a urine sample.

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Nafion‐multi‐walled Carbon Nanotubes Supported Tris(bipyridyl)iron(II) for Nicotine Detection

et al. 2022

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This work reports an electrochemical sensing framework for nicotine determination based on glassy carbon electrode (GC) immobilized with Fe(bpy)32+ (where bpy is 2,2’‐bipyridyl) supported by Nafion and multi‐walled carbon nanotubes (Nf‐MWCNTs). Fe(bpy)32+ immobilized Nf‐MWCNTs modified GC (GC/Nf‐MWCNTs/Fe(bpy)32+) manifests stable redox peaks, characteristics of Fe(bpy)32+. The GC/Nf‐MWCNTs/Fe(bpy)32+ exhibits effective electrochemical oxidation of nicotine, diminishing the overpotential relative to GC/Nf‐MWCNTs. The limit of detection is 0.1 μM (experimentally observed) with two different linear calibration ranges between 0.1 to 600 μM and 600 to 3000 μM. Electrocatalytic responses observed at GC/Nf‐MWCNTs/Fe(bpy)32+ indicate superior performance for nicotine determination with acceptable selectivity, stability, and reproducibility. Additionally, the nicotine present in real samples such as beedi and tobacco are also analyzed with satisfactory recovery percentages.

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Electrodeposition of Au nanoparticles on poly(diallyldimethylammonium chloride) functionalized reduced graphene oxide sheets for voltammetric determination of nicotine in tobacco products and anti-smoking pharmaceuticals

Abstract: The principal objective of this study was to develop a sensitive and selective electrochemical sensor for nicotine detection based on a novel PDDA-RGO/Au nanocomposite.

Cited by 14 publications

References 56 publications

Dual Signal Amplification Using Gold Nanoparticles-Enhanced Zinc Selenide Nanoflakes and P19 Protein for Ultrasensitive Photoelectrochemical Biosensing of MicroRNA in Cell

Dual Signal Amplification Using Gold Nanoparticles-Enhanced Zinc Selenide Nanoflakes and P19 Protein for Ultrasensitive Photoelectrochemical Biosensing of MicroRNA in Cell

A Novel Electrochemical Sensor for Detection of Nicotine in Tobacco Products Based on Graphene Oxide Nanosheets Conjugated with (1,2-Naphthoquinone-4-Sulphonic Acid) Modified Glassy Carbon Electrode

Nafion‐multi‐walled Carbon Nanotubes Supported Tris(bipyridyl)iron(II) for Nicotine Detection

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