2021
DOI: 10.1002/adfm.202170117
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Electrode Coatings: Partially Functional Electrode Modifications for Rapid Detection of Dopamine in Urine (Adv. Funct. Mater. 17/2021)

Abstract: In article number 2004146, Hadar Ben-Yoav and co-workers introduce a sensory device that can test unprocessed urine and quantify dopamine levels. By utilizing intelligent chemometric models for fingerprint identification, the device detects and separates overlapping electrochemical signatures in urine to arrive at its solution. Being able to rapidly detect the dopamine levels in urine is highly advantageous for early screening of neuroendocrine tumors.

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“…Electrochemical nonenzymatic detection of small molecule metabolites in biofluids (such as glucose, uric acid, hydrogen peroxide, etc . ), is a great clinical issue in early diagnostics of metabolic diseases. Advanced electrode materials are the central key for stable and sensitive detection. In particular, conductive polymers are considered as an ideal electrode candidate, due to tunable electronic conductivity, , versatile modifiability, environmental stability, , and favorable biocompatibility. , For instance, Abdul Amir Al-Mokaram et al designed a polypyrrole- (PPy-) coated ITO electrode using one-step electrodeposition for glucose biosensors applications. However, the linear range of this kind of electrode is relatively narrow.…”
Section: Introductionmentioning
confidence: 99%
“…Electrochemical nonenzymatic detection of small molecule metabolites in biofluids (such as glucose, uric acid, hydrogen peroxide, etc . ), is a great clinical issue in early diagnostics of metabolic diseases. Advanced electrode materials are the central key for stable and sensitive detection. In particular, conductive polymers are considered as an ideal electrode candidate, due to tunable electronic conductivity, , versatile modifiability, environmental stability, , and favorable biocompatibility. , For instance, Abdul Amir Al-Mokaram et al designed a polypyrrole- (PPy-) coated ITO electrode using one-step electrodeposition for glucose biosensors applications. However, the linear range of this kind of electrode is relatively narrow.…”
Section: Introductionmentioning
confidence: 99%
“…Until now, researchers have developed several high-performance analytical methods and sensors for the detection of ions, small molecules and biomolecules, such as fluorescence methods, and electrode-based electrochemical sensors. [10][11][12][13][14][15][16][17][18][19][20] These techniques and methods overcome the limitations of traditional analytical methods and provide insights into mole-cular detection. However, some existing analytical methods for GSH detection still require complicated labeling processes, which are expensive and time-consuming.…”
Section: Introductionmentioning
confidence: 99%