Recent studies of pressure flow relationships in isolated pulmonary valvular stenosis have demonstrated that, broadly speaking, they conform to certain well-known physical laws (Watson et al, 1960;Watson and Lowe, 1962), and a better understanding of right ventricular function in that condition has prompted us to make a similar study in patients with Fallot's tetralogy.Since there is still some disagreement about which cases should rightly be grouped under this title (Rosenblum et al, 1962;Coelho et al, 1961), we have considered only the so-called "classical" cases in our analysis: those with pulmonary stenosis, either valvular, infundibular, or both, and the characteristic ventricular septal defect that allows blood to pass freely from the right ventricle into an overriding aorta. When compared with those having a normal aortic root and an intact interventricular septum, it is obvious that the presence of this defect modifies the h1modynamic effects of obstruction to the outflow of blood from the right side of the heart.