Electroconvulsive Therapy for Anticholinergic and Benzodiazepine Nonresponsive Tardive Oculogyric Crisis: A Case Report

Cheng, Kai-Jen; Yeh, Ta‐Chuan; Ku, Shih-Chieh; Tseng, Yu‐Ting; Liang, Chih‐Sung

doi:10.1097/mjt.0000000000000971

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…In our case, the initial step required the removal of the offending agent or the reduction of its dosage. In cases where this is not possible, administration of anticholinergics, such as benztropine or antihistamines, is used [14]. Repeated administration after 15 to 30 minutes may be needed [15].…”

Section: Discussionmentioning

confidence: 99%

Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female

Wilson

Filatov

Azhar

et al. 2020

Cureus

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Oculogyric crisis is a rare ocular dystonia first appearing at the turn of the last century in postencephalitic patients. In the modern era, they were most frequently associated with firstgeneration D1 dopaminergic receptor blocking antipsychotic medication. We present an unusual case of acute oculogyric crisis in a 74-year-old woman with longstanding Parkinson disease following exposure to the second-generation neuroleptic ziprasidone, which has dopaminergic (D2) and serotoninergic (5-HT2A) receptor blocking effects and is used for severe delusions and psychosis. To the best of our knowledge, there are no other published reports.

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Section: Discussionmentioning

confidence: 99%

Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female

Wilson

Filatov

Azhar

et al. 2020

Cureus

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“…37 Electro-convulsive therapy can also be given in tardive OGC cases with psychotic disorders. 55 Prophylactic use of anticholinergic drugs for 1-2 weeks is indicated in patients with greater vulnerability for OGC with certain antipsychotics, though the available guidelines are inconsistent for the duration of use of such prophylactic agents. 49 Levodopa may be useful in Parkinson's disease with OGC.…”

Section: Mechanism Of Ogcmentioning

confidence: 99%

Spotlight on Oculogyric Crisis: A Review

Mahal

Suthar

Nebhinani

2020

Indian Journal of Psychological Medicine

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Background: Oculogyric crisis (OGC) is a form of acute dystonia characterized by sustained dystonic, conjugate, and upward deviation of the eyes. It was initially reported in patients with postencephalitic parkinsonism. But later, other factors such as medications, movement disorders, metabolic disorders, and focal brain lesions were also found to be associated with OGC. Methods: The literature regarding OGC was searched via PubMed, Google Scholar, and through citations in relevant articles till December 2019, with keywords including OGC, oculogyric eye movements, tonic eye movement, neuroleptics and OGC, antipsychotics and OGC, and all combinations of these. Only original articles (abstract or full text) that were published in the English language were reviewed. Results: Hypodopaminergic state is implicated in the pathogenesis of OGC. Common risk factors are younger age, male sex, severe illness, high neuroleptic dose, parenteral administration of neuroleptics, high potency of neuroleptic drugs, abrupt discontinuation of anticholinergic medication, and family history of dystonia. Conclusion: OGC is an acute dystonic reaction leading to tonic upward deviation of eyes. It is associated with various neurometabolic, neurodegenerative, and movement disorders and medications such as antipsychotics, antiemetics, antidepressants, antiepileptics, and antimalarials. OGC can adversely impact the compliance and prognosis of the primary illness. Hence, it needs to be managed at earlier stages with appropriate medication, primarily anticholinergics.

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Multiple drugs

2021

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Electroconvulsive Therapy for Anticholinergic and Benzodiazepine Nonresponsive Tardive Oculogyric Crisis: A Case Report

Cited by 3 publications

References 5 publications

Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female

Ziprasidone-Induced Oculogyric Crisis in a 74-Year-Old Female

Spotlight on Oculogyric Crisis: A Review

Multiple drugs

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