Abstract:Many studies report that the electroconvulsive seizure (ECS) administered immediately after the training (fear conditioning) impairs the memory formation. In contrast, there are only few studies asking whether or not the ECS before the training influence the learning. Here, we trained mice by fear conditioning and investigated which timing of the ECS abrogates the memory formation. Contextual and auditory memories were tested 1 h, 24 h, and 8 d after the conditioning to assess the formation of short-(STM) and … Show more
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