“…[94][95][96][97][98] Furthermore, based on this work, there are some alternative matrigel that have positive effects on cell characteristics for cell culture or organoid culture, such as gelatin, chitosan, polycaprolactone, collagen, polyethylene glycol, hyaluronic acid, ceria nanoparticle, graphene oxide, alginate, and carbon nanotubes. 51,52,[55][56][57][58]63,[74][75][76][77][78][79][81][82][83]88,90,93,[95][96][97] Besides that, some alternative matrigel showed negative effects on cell characteristics, such as gelatin, collagen, matrigel, optimization manuka honey, and benzo [a] pyrene (B (a) P)-loaded polystyrene microplastics, as summarized in Table 2B. 80,89,91,92,94,98 Interestingly, graphene oxide has no negative effects on cell characteristics at a certain content.…”