“…A large number of studies using MPc as electron mediators in electrochemical sensors have been reported, the mediation properties varying with the structure of the Pc macrocycle, , the metal center, , substrate, − or technique used for film formation. − MPc can also be used as substitutes for natural proteins, acting as the active center of an enzyme molecule with the same efficiency and selectivity . Electrode modification with MPc has been carried out by different methods, such as Langmuir–Blodgett (LB), ,− electrostatic layer-by-layer (LbL), , physical vapor deposition (PVD), ,, casting, and electrochemical deposition. , Recently, adsorption by click chemistry in carbon nanotube layers has been described. , Distinct behaviors of films on the same electrode substrate may be achieved through different deposition methods, enabling the development of chemical/electrochemical sensors with tunable properties …”