Electrochemiluminescence Sensor Based on N-Doped Carbon Quantum Dots for Determination of Ceftazidime in Real Samples

Abstract

We report an electrochemiluminescence (ECL) sensor based on nitrogen doped carbon quantum dots (N-CQDs), which has been synthesized by a solvothermal method. The N-CQDs were characterized using various techniques such as high-resolution transmission electron microscopy, field emission scanning electron microscopy, UV-Vis absorption and photoluminescence spectroscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and X-ray diffraction. The potential sweep range (−0.5 to −2.2 V) shows a stable and strong ECL signal. Interestingly, the ECL intensity only decreased by less than 20% after storing at 4°C for 10 months. The applicability of the N-CQD sensor in electroanalytical chemistry was identified by the linear ECL on–off response for ceftazidime in a concentration range from 1×10-7 to 5×10-4 mol L–1 and a detection limit of 2.3×10-8 mol L–1. The results suggest that the proposed ECL sensor is robustly applicable for analysis of ceftazidime in real samples such as human serum, bovine milk, and commercial milk powder.

A new plant-esterase inhibition based electrochemical sensor with signal amplification by MoS2@N-CDs for chlorpyrifos detection

“…This is due to the decrease in lattice spacing resulting in a larger angle of the diffraction peaks, which proves that the CDs are doped with nitrogen atoms between the crystal planes. 26 In the XRD pattern of MoS 2 , the three diffraction peaks appearing at 14.6°, 31.6°, and 56.1° correspond to the (002), (100), and (110) diffraction crystal planes of MoS 2 , respectively. And in the XRD pattern of MoS 2 @N-CDs, three diffraction peaks also appeared, which belonged to the (002), (100) and (110) diffraction crystal planes of MoS 2 .…”

WITHDRAWN: Electrospun Pullulan-based Nanofibers to Prepare Modified Electrodes for Electrochemiluminescence Detection of Azithromycin

“…The sensitivity of electrochemiluminescence analysis is mainly determined by the electrochemical properties of nanomaterials with modi ed electrodes. The carbon material which can be used for modifying the electrode include carbon quantum dots (N-CQDs) [19,20], graphene [21], carbon nanotubes [22,23] and carbon nano bers [24,25] etc. Nanoscale carbonaceous materials, especially carbonnanotubes (CNTs) and carbon nano bers (CNFs), have attracted great research interests in the electroanalysis eld [26].…”

Synthesis and Photoelectric Properties of Nitrogen‐ and Phosphorus‐Doped Carbon Quantum Dots

“…[ 23 ] For example, Afshary et al used citric acid (CA) and urea as precursors to synthesize N‐CQDs by solvothermal method for ECL sensors. [ 24 ] Liu et al synthesized four N‐doped CQDs by hydrothermal method, using CA as carbon source and urea, ethylenediamine (EDA), ammonia solution (AS), and melamine as nitrogen sources, respectively. [ 25 ] Rafiee et al used chitosan (CHIT) as a green carbon source rich in nitrogen to prepare chitosan CQDs by hydrothermal method and then magnetized Fe 3 O 4 nanoparticles to prepare magnetic chitosan CQD nanoparticles (Fe 3 O 4 @CQD NPs).…”