Electrochemiluminescence biosensor for microRNA determination based on AgNCs@MoS2 composite with (AuNPs-Semicarbazide)@Cu-MOF as coreaction accelerator

Recent Progress in Phase Regulation, Functionalization, and Biosensing Applications of Polyphase MoS2

“…prepared an ECL biosensor for miNA‐162A using silver nanoclusters/MoS 2 (AgNCs@MoS 2 ) as ECL material, sodium bisulfite (S 2 O 8 2− ) as coreactant, and semicarbazone (Sem) as coreaction accelerator. [ 220 ] Notably, the presence of Sem accelerated the reduction of the S 2 O 8 2− and led to the formation of more oxidized intermediate SO 4 2− , thus amplifying the ECL signal. In the ECL adaptor sensing strategy constructed by Liu et al., RET and coreaction accelerator were simultaneously used to enhance ECL efficiency.…”

“…) as coreactant, and semicarbazone (Sem) as coreaction accelerator. [220] Notably, the presence of Sem accelerated the reduction of the S 2 O 8 2− and led to the formation of more oxidized intermediate SO 4…”

Recent progress of metal nanoclusters in electrochemiluminescence

“…In the hybrids, MoS 2 possessed both superior electron conduction as the electrode matrix and a large specific surface area for abundant AgNC loading. 71 In another work, large numbers of BSA-AuNCs were attached to amino-functionalized silica nanocarriers via EDC/sulfo-NHS chemistry and used for highly efficient solid-state ECL. 72 Self-accelerating architecture.…”

“…37 Besides, Li and co-workers designed an ECL genosensor for miRNA-162a determination derived from the ECL system of AgNCs@MoS 2 /S 2 O 8 2− /semicarbazide and a CHA-induced target recycling strategy. 71…”

Nucleic acid isothermal amplification-based soft nanoarchitectonics as an emerging electrochemical biosensing platform

“…108 For example the construction of Hf-ETTC, metalorganic layer, 109 carbon dots, 110,111 copper nanoclusters (Cu NCs), 112 click chemistry-driven bioanalysis using AuAg nanoclusters, 113 graphite phase carbon nitride (g-C 3 N 4 ), [114][115][116][117] and AgNCs@MoS 2 . 118 In order to improve the ECL sensing application in terms of good chemical stability and activity, less toxicity or visible light emissions, further improved and efficient nanomaterials were reported such as nitrogen vacancy-rich carbon nitride nanosheets (NV-CN). 119 Different from the ECL emission of graphitic carbon nitride at less than 470 nm, 120 NV-CN holds stable and highly improved blue-green ECL emis- sions, avoiding the problem of electrode passivation by trapping the excess electrons in the NV sites, and thus realized as an enhanced ECL aptasensor.…”