Electrochemically reduced graphene oxide/Poly-Glycine composite modified electrode for sensitive determination of l-dopa

Palakollu, Venkata Narayana; Thapliyal, Neeta; Chiwunze, Tirivashe E.; Karpoormath, Rajshekhar; Karunanidhi, Sivanandhan; Cherukupalli, Srinivasulu

doi:10.1016/j.msec.2017.03.173

Cited by 37 publications

(25 citation statements)

References 37 publications

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“…At higher frequency, the semicircular diameter is equal to the charge transfer resistance (Rct) which is related with the electron transfer kinetic. The Rct value was affected by the electrode surface modification . The semicircle diameters of bare GCE, Poly(TAU)/GCE and Pd/Poly(TAU)/GCE were obtained as 556 Ω, 239 Ω and 101 Ω, respectively.…”

Section: Resultsmentioning

confidence: 99%

Enhanced Electrochemical Determination of Catechol and Hydroquinone Based on Pd Nanoparticles/Poly(Taurine) Modified Glassy Carbon Electrode

Koçak

2019

Electroanalysis

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Here, Pd nanoparticles and poly(taurine) film was prepared on the glassy carbon electrode surface (Pd/Poly(TAU)/GCE) by the rapid electrochemical technique. The proposed composite surface was characterized by scanning electron microscopy(SEM), X‐ray photoelectron spectroscopy(XPS) and electrochemical impedance spectroscopy(EIS). Enhanced electron transfer ability and higher electroactive surface area were achieved at Pd/Poly(TAU)/GCE as compared to the bare GCE and polymer film electrode. The new and highly stable Pd/Poly(TAU)/GCE was employed for the individual and simultaneous determination of hydroquinone and catechol which were environmentally toxic. Under the optimized conditions, HQ and CC were individually determined by using the differantial pulse voltammetry in the linear ranges of 0.008–100 μM and 0.001–100 μM with the detection limits of (LOD) 2.1 nM and 0.68 nM, respectively. In case of simultaneous determination, LODs were found as 10 nM and 0.88 nM for HQ and CC, respectively. The content of both analytes in the real sample analysis was evaluated in the river water and tap water successfully.

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Section: Resultsmentioning

confidence: 99%

Enhanced Electrochemical Determination of Catechol and Hydroquinone Based on Pd Nanoparticles/Poly(Taurine) Modified Glassy Carbon Electrode

Koçak

2019

Electroanalysis

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“…In EIS spectra, the Nyquist plot comprises of a semicircle at high frequency region. The diameter of the semicircle is equal to the interfacial charge transfer resistance (R ct ) . Figure depicts the EIS spectra recorded at bare GCE, AuNPs/GCE and AuNUs/GCE in the presence of 2.5 mM [Fe(CN) 6 ] 3− /[Fe(CN) 6 ] 4− (1:1) in 0.1 M KCl.…”

Section: Resultsmentioning

confidence: 99%

A Simple, Efficient and Ultrasensitive Gold Nanourchin Based Electrochemical Sensor for the Determination of an Antimalarial Drug: Mefloquine

et al. 2017

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Mefloquine (MQ) is a quinoline based antimalarial drug, which is potent against multiple drug‐resistant Plasmodium falciparum. It is widely prescribed for the prophylactic treatment of malaria. Due to extensive usage of MQ, constant monitoring of the drug level in human body is of paramount importancein order to ensure that optimum drug exposure is achieved. The present work describes a gold nanourchins (AuNUs) based electrochemical sensor for the determination of MQ.AuNUs were synthesized via seed‐mediated method and characterized using ultraviolet‐visible spectroscopy, energy‐dispersive X‐ray spectroscopy, field emission scanning electron microscopy, zeta‐sizer and electrochemical techniques (electrochemical impedance spectroscopy and cyclic voltammetry). Fabrication of the sensor was done by drop‐coating the synthesized AuNUs onto a glassy carbon electrode. The fabricated sensor exhibited enhanced voltammetric response, which was attributed to the excellent conductivity and high surface area of AuNUs. Under optimum square wave voltammetric conditions, the sensor displayed two linear response ranges (from 2.0×10−9 to 1.0×10−6 M and from 1.0×10−6 to 1.0×10−3 M) with a detection limit of 1.4 nM. The electrode demonstrated good reproducibility, stability and selectivity over common interferents. The utility of the sensor was successfully assessed for quantification of the drug in pharmaceutical preparation and spiked human urine sample. Thus, the present study demonstrates a promising approach for determination of MQ with practical utility in quality control and clinical analysis.

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“…The electrochemical reduction of rGO by MPA is not described in the literature. However, based on the procedure via amperometry and by cyclic voltammetry [18][19][20][21][22], some conditions were adopted as a starting point. According to the literature review, [22] the application of a negative potential after the reduction process using cyclical voltammetry tends to improve the reduction and homogeneity of the film, with this in mind and in order to enjoy the best performance possible of the MPA technique was adopted 9 potentials for the process of reduction of GO, optimizing which would be these potentials, the time of application and the concentration of GO.…”

Section: Multiple Pulse Amperometrymentioning

confidence: 99%

An Electrochemical Sensor Based on Electroreduction of Graphene Oxide on a Glassy Carbon Electrode Using Multiple Pulse Amperometry for Simultaneous Determination of L-Dopa and Benserazide

Barbosa¹,

Oliveira²,

Pereira³

2020

Graphene Production and Application

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In this work, we described the development an electrochemical sensor based on electroreduction of graphene oxide (rGO) on a glassy carbon electrode (GCE) for simultaneous determination of l-Dopa and benserazide. For the elaboration of the GCE/rGO, the developed methodology was based on the electrochemical technique: multiple pulse amperometry (MPA). The MPA was more stable and efficient for the formation of rGO film, under optimum conditions (pH 6.00; concentration of rGO 2.00 mg mL −1 ; time 450 s; potentials −0.60, −0.70, −0.80, −0.90, −0.95, −1.00, −1.10, −1.20, and -1.30 V). After the film was formed, the cyclic voltammetry was used to detect LD and BZ in real samples and optimized conditions 0.05 mol L −1 PBS (pH 5.50). The linear range for the LD is 25-425 μmol L −1 and the BZ of 5-80 μmol L −1 . The limit of detection calculated was 17.10 (LD) and 2.99 (BZ) μmol L −1 .

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Electrochemically reduced graphene oxide/Poly-Glycine composite modified electrode for sensitive determination of l-dopa

Cited by 37 publications

References 37 publications

Enhanced Electrochemical Determination of Catechol and Hydroquinone Based on Pd Nanoparticles/Poly(Taurine) Modified Glassy Carbon Electrode

Enhanced Electrochemical Determination of Catechol and Hydroquinone Based on Pd Nanoparticles/Poly(Taurine) Modified Glassy Carbon Electrode

A Simple, Efficient and Ultrasensitive Gold Nanourchin Based Electrochemical Sensor for the Determination of an Antimalarial Drug: Mefloquine

An Electrochemical Sensor Based on Electroreduction of Graphene Oxide on a Glassy Carbon Electrode Using Multiple Pulse Amperometry for Simultaneous Determination of L-Dopa and Benserazide

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