Electrochemically Driven Nickel‐Catalyzed Halogenation of Unsaturated Halide and Triflate Derivatives
Ming‐Yu Chen,
Sylvain Charvet,
Pierre‐Adrien Payard
et al.
Abstract:A robust electrochemically driven nickel‐catalyzed halogen exchange of unsaturated halides and triflates (Br to Cl, I to Cl, I to Br, and OTf to Cl) is reported. A combination of NiCl2 ⋅ glyme as the precatalyst, 2,2′‐bipyridine as a ligand, NMP as the solvent, and electrochemistry allowed the generation of a nickel species that promotes reductive elimination of the desired product. This paired electrochemical halogenation is compatible with a range of unsaturated halides and triflates, including heterocycles,… Show more
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