Electrochemical stability and cell response of nanostructures elaborated on zirconium

Abstract

The paper studies the electrochemical stability in physiological serum and cell response of nanostrucures obtained on Zr by anodizing in electrolytes containing fluorinated ethylene glycol and various amounts of K2CO3. SEM analysis revealed that the porous nanostructure formation is greatly influenced by the various K2CO3 concentrations in the electrolyte by tipping the balance between oxide formation and dissolution during the anodizing process. The porosities of the samples were evaluated from polarization resistances recorded in physiological serum. Chronoamperometric measurements were employed to establish a range of compactness for the samples. It was found that the amount of K2CO3 from the electrolyte is directly responsible in obtaining oxide strata more resistant to corrosion. All tests performed on the samples such as corrosion, hydrophylicity and cell viability with MC3T3‐E1 pre‐osteoblasts cells from mouse bones revealed that the best coating for future research regarding nanostructured Zr implants was the one obtained from the electrolyte containing the highest amount of K2CO3.

Present and Future of ZrO2 Nanostructure as Reservoir for Drug Loading and Release

“…The anodization process in the fluoride-containing electrolyte resulted in the formation of a porous nanostructured surface that showed improved electrochemical stability and cell adhesion compared to the other electrolytes. This result suggests that these surfaces have potential applications in biomedical implants and devices, where biocompatibility and corrosion resistance are crucial factors [101].…”

The influence of oxygen amount in oral cavity media on the corrosion behavior of nanostructures formed on anodized Zr

“…Next, the specimens were rinsed with distilled water and dried in atmosphere. The bath composition and anodizing conditions were chosen on the basis of our previous study of anodic oxidation of zirconium in carbonate . The process was carried out using a DC power supply (Matrix MPS‐7505L‐1).…”

“…[17] The better resistance to corrosion of the nanotube layer was put in evidence as well. [17,18] To our best knowledge, the corrosion resistance of nanotube layers in saliva with various amount of oxygen was not investigated until now. It is the aim of this paper and its novelty to modify the amount of oxygen in Afnor saliva and to establish a range of stability of zirconia nanotubes as a function of oxygen content.…”

“…Under suitable voltage, the degree of pore formation reaches a steady‐state, resulting in the whole porous structure formation as an intermediate stage of nanotube fabrication. The electrochemical stability in physiological serum and cell response of nanostrucures elaborated on Zr leading to various porosity was the subject of a previous paper . The better resistance to corrosion of the nanotube layer was put in evidence as well .…”

“…The electrochemical stability in physiological serum and cell response of nanostrucures elaborated on Zr leading to various porosity was the subject of a previous paper . The better resistance to corrosion of the nanotube layer was put in evidence as well . To our best knowledge, the corrosion resistance of nanotube layers in saliva with various amount of oxygen was not investigated until now.…”