Electrochemical sensor for dodecyl gallate determination based on electropolymerized molecularly imprinted polymer

Abstract

An electrochemical sensor based on molecularly imprinted polymer (MIP) film for dodecyl gallate detection at the surface of a glassy carbon electrode (GCE) was proposed in this paper. The GCE was modified with f-MWCNT and the MIP synthesis was performed in situ by means of electropolymerization using ortho-phenylenediamine as the monomer. The stepwise preparation of the MIP and NIP (non-imprinted polymer) was characterized electrochemically by means of cyclic and square wave voltammetry employing ferrocyanide/ferricyanide as a redox probe. The selective capacity performance of the MIP and its imprinted effect to the template molecule (analyte) was compared to the NIP. They were also characterized by scanning electron microscopy technique (SEM). The analytical performance of the MIP sensor performed using square wave voltammetry showed linear range from 0.50 to 8.0 × 10 −9 mol L −1 , with a correlation coefficient of 0.9921. The sensor presented detection and quantification limit of 0.22 × 10 −9 and 0.67 × 10 −9 mol L −1 , respectively. The apparent dissociation constant (K D) calculated was of 1.26 × 10 −4 mol L −1 and 5.27 × 10 −1 mol L −1 for the MIP and NIP respectively.

Electrochemical sensing of ecstasy with electropolymerized molecularly imprinted poly(o-phenylenediamine) polymer on the surface of disposable screen-printed carbon electrodes

“…Following polymerization, the template molecule is removed, and the MIP is manufactured, it now possesses spots complementary in shape, size, and functionality to the imprinted molecule. Electrochemical MIPs are a special kind of MIPs, which synergistically combine the MIPs' advantages (in particular their selectivity) with the inherent gains of electrochemical sensors, like simplicity, sensitivity, portability, speed of analysis and user-friendliness, these are important key features in forensics [35][36][37]. Electropolymerization has been the correct choice especially in the preparation of MIPs with electroanalytical sensing, it enables a simple way of controlling the polymers thickness and morphology, it is reproducible and permits polymerization in an aqueous media [38][39][40][41].…”

Electrochemical sensing of the thyroid hormone thyronamine (T0AM) via molecular imprinted polymers (MIPs)

“…Although there can be found in literature a few works with MIPs developed for T4 [15,16], authors are not aware of any similar developments for T 0 AM. Electrochemical MIP-based sensors combine the advantages of MIPs (mainly their selectivity) with the advantages inherent to electrochemical sensors namely: portability, speed of analysis, user-friendliness, simplicity and sensitivity [17], these can be powerful tools for point-of-care applications [18][19][20].…”

Synthesis and characterization of magnetic-molecularly imprinted polymers for the HPLC-UV analysis of ametryn

“…MIPs recently evolved to magnetic MIPs (mag-MIPs), these particles improve the separation and opened a new window for analyzing compounds in complex sample matrices [24]. Among other advantages, these hybrid materials offer enhanced selectivity, durability, and the possibility of reuse [25][26][27][28][29]. Recent reviews detail the wige range of possibilities using these interesting materials [30][31][32].…”