Electrochemical sensor based on molecularly imprinted polymer cryogel and multiwalled carbon nanotubes for direct insulin detection

Wardani, Nur Indah; Kangkamano, Tawatchai; Wannapob, Rodtichoti; Kanatharana, Proespichaya; Thavarungkul, Panote; Limbut, Warakorn

doi:10.1016/j.talanta.2022.124137

Cited by 16 publications

(10 citation statements)

References 56 publications

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“…At the same time, the cryogel MIP provides selective recognition of the analyte. Measurements in human serum samples using SWV gave similar results as a commercial electrochemiluminescence immunoassay [134]. Shao et al developed a sensor consisting of MIP on a GC electrode modified with AuNPs and MXene for tetrabromobisphenol A detection.…”

Section: Aliphatic/non-aromatic Monomersmentioning

confidence: 80%

“…Popular detection methods include DPV (e.g., [35,45,60]) and CV (e.g., [54,90,108]). Other examples utilize square wave voltammetry [40,94,110,134] or linear sweep voltammetry [83]. Amperometric sensors comprising cMIPs [33,34,38,39] are less common.…”

Section: Transducersmentioning

confidence: 99%

“…Melamine has been used as a fake protein source in infant formula and pet food in China. It is connected to acute renal failure in animals General overview of the different application areas of cMIP-based sensors, cited from [32][33][34][35]37,39,40,42,43,45,47,48,[54][55][56]58,63,66,67,[76][77][78]88,[91][92][93][95][96][97]101,105,107,116,119,120,122,124,[127][128][129]134,135,137,139,140].…”

Section: Food Safetymentioning

confidence: 99%

“…Figure 6.General overview of the different application areas of cMIP-based sensors, cited from[32][33][34][35]37,39,40,42,43,45,47,48,[54][55][56]58,63,66,67,[76][77][78]88,[91][92][93][95][96][97]101,105,107,116,119,120,122,124,[127][128][129]134,135,137,139,140].…”

mentioning

confidence: 99%

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Conductive Molecularly Imprinted Polymers (cMIPs): Rising and Versatile Key Elements in Chemical Sensing

et al. 2023

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Molecularly imprinted polymers (MIPs) have proven useful as receptor materials in chemical sensing and have been reported for a wide range of applications. Based on their simplicity and stability compared to other receptor types, they bear huge application potential related to ongoing digitalization. This is the case especially for conductive molecularly imprinted polymers (cMIPs), which allow easy connection to commercially available sensing platforms; thus, they do not require complex measuring setups. This review provides an overview of the different synthetic approaches toward cMIPs and the obtained limit of detections (LODs) with different transducing systems. In addition, it presents and discusses their use in different application areas to provide a detailed overview of the challenges and possibilities related to cMIP-based sensing systems.

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Section: Aliphatic/non-aromatic Monomersmentioning

confidence: 80%

Section: Transducersmentioning

confidence: 99%

Section: Food Safetymentioning

confidence: 99%

mentioning

confidence: 99%

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Conductive Molecularly Imprinted Polymers (cMIPs): Rising and Versatile Key Elements in Chemical Sensing

et al. 2023

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“…Artificial MIP receptors have also shown promise for highly sensitive, low-cost decentralized insulin measurements 73 , 74 . Efforts in 2022 towards developing wearable stimuli-responsive reversible MIP sensors for continuous metabolites and nutrients monitoring look encouraging for the future emergence of wearable CIM devices 75 , 76 .…”

Section: Biosensors For Decentralized Insulin Monitoringmentioning

confidence: 99%

Insulin detection in diabetes mellitus: challenges and new prospects

et al. 2023

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Tremendous progress has been made towards achieving tight glycaemic control in individuals with diabetes mellitus through the use of frequent or continuous glucose measurements. However, in patients who require insulin, accurate dosing must consider multiple factors that affect insulin sensitivity and modulate insulin bolus needs. Accordingly, an urgent need exists for frequent and real-time insulin measurements to closely track the dynamic blood concentration of insulin during insulin therapy and guide optimal insulin dosing. Nevertheless, traditional centralized insulin testing cannot offer timely measurements, which are essential to achieving this goal. This Perspective discusses the advances and challenges in moving insulin assays from traditional laboratory-based assays to frequent and continuous measurements in decentralized (point-of-care and home) settings. Technologies that hold promise for insulin testing using disposable test strips, mobile systems and wearable real-time insulin-sensing devices are discussed. We also consider future prospects for continuous insulin monitoring and for fully integrated multisensor-guided closed-loop artificial pancreas systems.

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