Electrochemical Oxidation of Meloxicam and Its Determination in Tablet Dosage Form

Spectrofluorimetric and Spectrophotometric Stability-Indicating Methods for Determination of Some Oxicams Using 7-Chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD-Cl)

“…For Tx, different methods were reported including spectrophotometric, 6,[11][12][13] fluorimetric, [13][14][15] infrared, 16) electrochemical [17][18][19] and HPLC 8,20) methods. For Mx, spectrophotometric, 6,13,[21][22][23] fluorimetric, 13,24) electrochemical 25,26) and HPLC 8,23,27,28) methods were reported. Among the various methods available for the determination of drugs, spectrophotometry and spectrofluorimetry continue to be very popular, because of their simplicity, specificity and low cost.…”

Differential Pulse Anodic Voltammetric Determination of Tiapride Hydrochloride in Pharmaceutical Preparation and Human Urine Using Carbon Paste Electrodes

“…The peak potential shifted to more positive values with increasing the scan rate. The suggested mechanism for the anodic oxidation of the amide group is that described by Radi et al 19 It starts by one electron oxidation to form the cation radical at the nitrogen atom; this is followed by a rapid loss of a second electron and proton to give the iminium ion, to which the water is subsequently added. Therefore, the oxidation of TiapCl at carbon paste electrodes is an irreversible diffusion-controlled process with some kinetic control.…”

“…The robustness 19 of the proposed method was examined by evaluating the effect of small changes in some of the most important procedure parameters, including the pH of the Britton-Robinson (BR) buffer (6.9 -7.1) and the pulse amplitude (98 -102 mV). None of the changes significantly affect the drug recovery (Table 2); consequently, the optimized procedure was reliable for the assay of TiapCl and it could be considered robust.…”

A dysprosium nanowire modified carbon paste electrode for determination of levodopa using fast Fourier transformation square-wave voltammetry method

“…That is based on the equation of 0.0592(h/n) V/pH, where h and n are the number of protons and electrons involved in the electrode process [23].This is in accordance with literature data about mechanistic scheme of some catechol groups compounds to changed hydroxyl group to quinon group [24]. For analytical purposes, the medium chosen to carry out further studies was the 0.05 mol l-1 acetate buffer solution at pH 7.0.…”