Electrochemical impedance spectroscopy and quartz crystal nanobalance (EQCN) studies of insulin adsorption on Pt

Wright, Jennifer E. I.; Cosman, Nicholas P.; Fatih, Khalid; Omanovic, Sasha; Roscoe, Sharon G.

doi:10.1016/j.jelechem.2003.10.031

Cited by 36 publications

(36 citation statements)

References 33 publications

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“…2-4 (see below) are given in Table 1. The cell resistance R was around 38 cm 2 for experiments in the presence of O 2 and 42 cm 2 in the experiments carried out in the absence of O 2 . An equivalent circuit with two parallel RC combinations, corresponding to a surface partly covered by oxide and partly by protein, in series with an RCPE representing the interface with solution was also tested, but without improved fitting.…”

Section: Impedance Spectramentioning

confidence: 96%

“…A number of papers have reported the application of the electrochemical QCM (EQCM), usually together with voltammetry, electrochemical impedance spectroscopy (EIS) or surface analysis techniques [1][2][3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

“…The adsorption of insulin on platinum was studied by simultaneous cyclic voltammetry and EQCM measurements and by EIS [2]. The adsorption of BSA on gold and platinum was probed by simultaneous EIS and QCM measurements in Britton-Robinson buffer with the ferri/ferrocyanide couple as redox probe [3]; it was found that BSA adsorption successfully inhibits gold corrosion during the oxidation of hexacyanoferrate (II).…”

Section: Introductionmentioning

confidence: 99%

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Interaction of BSA protein with copper evaluated by electrochemical impedance spectroscopy and quartz crystal microbalance

Pinto

Soares

Brett

2008

Electrochimica Acta

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The interaction of bovine serum albumin (BSA) protein with copper in phosphate buffer solution has been studied by a combination of electrochemical impedance spectroscopy (EIS) close to the open circuit potential, with simultaneous monitoring by the electrochemical quartz crystal microbalance (EQCM), in order to throw light on BSA adsorption. Copper films were electroplated onto gold quartz crystals and mounted in the EQCM. Experiments were conducted in the presence and absence of dissolved oxygen and of BSA and the results show the influence of O 2 on the protein/metal interaction and also show specific interactions between BSA and copper. The good reproducibility obtained in these experiments suggests future application to other systems and which should lead to a better understanding of the use of such types of protein as corrosion inhibitors.

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Section: Impedance Spectramentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Interaction of BSA protein with copper evaluated by electrochemical impedance spectroscopy and quartz crystal microbalance

Pinto

Soares

Brett

2008

Electrochimica Acta

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“…7), as described in our previous manuscripts for a variety of proteins [41,64,65]. The data was normalized by setting the frequency change, which fluctuated randomly with each protein addition, at the same value obtained with the phosphate buffer alone at À0.6 V, which represented the lowest potential used before the onset of hydrogen evolution, in accordance with the method described by Jerkiewicz et al [66].…”

Section: Electrochemical Quartz Crystal Nanobalancementioning

confidence: 99%

A comparative study of electrochemical techniques in investigating the adsorption behaviour of fibrinogen on platinum

Farcas

Cosman

Ting

et al. 2010

Journal of Electroanalytical Chemistry

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“…Roscoe et al [29] studied the adsorption of insulin on platinum electrodes as one of the processes for designing artificial pancreas. The same group used EIS to study adsorption of a-lactoalbumin and b-casein on stainless steel [30].…”

Section: Eis In Biomedical Engineeringmentioning

confidence: 99%

Impedance Spectroscopy: A Powerful Tool for Rapid Biomolecular Screening and Cell Culture Monitoring

2005

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Dielectric spectroscopy or Electrochemical impedance spectroscopy (EIS) is traditionally used in corrosion monitoring, coatings evaluation, batteries, and electrodeposition and semiconductor characterization. However, in recent years, it is gaining widespread application in biotechnology, tissue engineering, and characterization of biological cells, disease diagnosis and cell culture monitoring. This article discusses the principles and implementation of dielectric spectroscopy in these bioanalytical applications. It provides examples of EIS as label-free, mediator-free strategies for rapid screening of biocompatible surfaces, monitoring pathogenic bacteria, as well as the analysis of heterogeneous systems, especially biological cells and tissues. Descriptions are given of the application of nanoparticles to improve the analytical sensitivities in EIS. Specific examples are given of the detection of base pair mismatches in the DNA sequence of Hepatitis B disease, TaySachs disease and Microcystis spp. Others include the EIS detection of viable pathogenic bacteria and the influence of nanomaterials in enhancing biosensor performance. Expanding applications in tissue engineering such as adsorption of proteins onto thiolated hexa(-ethylene glycol)-terminated (EG6) self-assembled monolayer (SAM) are discussed.

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Electrochemical impedance spectroscopy and quartz crystal nanobalance (EQCN) studies of insulin adsorption on Pt

Cited by 36 publications

References 33 publications

Interaction of BSA protein with copper evaluated by electrochemical impedance spectroscopy and quartz crystal microbalance

Interaction of BSA protein with copper evaluated by electrochemical impedance spectroscopy and quartz crystal microbalance

A comparative study of electrochemical techniques in investigating the adsorption behaviour of fibrinogen on platinum

Impedance Spectroscopy: A Powerful Tool for Rapid Biomolecular Screening and Cell Culture Monitoring

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