Electrochemical grafting by reduction of 4-aminoethylbenzenediazonium salt: Application to the immobilization of (bio)molecules

Construction of DNA biosensor at glassy carbon surface modified with 4-aminoethylbenzenediazonium salt

“…This may indicate that the grafted amino groups are protonated and form a positively charged film at the electrode surface. The protonation of the covalently bound AEBD salt at pH = 7.4 was also suggested by Griveau et al (Griveau et al, 2007). The formation of a positively charged film contributes also to a decrease of the charge transfer resistance of a negatively charged redox probe.…”

“…The synthesis of 4-aminoethylbenzenediazonium tetrafluoroborate (AEBD) was done according to the procedure described in the literature (Griveau et al, 2007). More details about synthesis are given in Supporting Information.…”

Electro-reduction of diazonium salts on gold: Why do we observe multi-peaks?

“…The reduction of diazonium salts was also performed on gold [2,[11][12][13], but to the best of our knowledge, no observation of multipeaks was yet reported, although shoulders are observable on the curves reported in Ref. [12].…”

Covalent Modification of Glassy Carbon Surfaces by Using Electrochemical and Solid‐Phase Synthetic Methodologies: Application to Bi‐ and Trifunctionalisation with Different Redox Centres

“…[27,[35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50] The main strategy consists of immobilising a 4-nitrophenyl group at the carbon surface by reducing the corresponding diazonium salt, reducing the nitro group to an amine group, then allowing subsequent chemical modifications. [27,35,36,41,43,48,50] Other examples include the immobilisation of a 4-carboxyphenyl group, [39,42,46,47] 4-(chloromethyl)phenyl group, [37,38] 4-(aminoethyl)phenyl group, [40] and more recently phenylmaleimide group, [44] phenylazide or phenylacetylene groups, [45] and boronic acid group, [49] followed by further chemical modification at the reactive groups for the preparation of single modified carbon A C H T U N G T R E N N U N G electrodes.…”