Electrochemical Fluorination

Abstract

Recent studies on electrochemical fluorination of organic molecules and macromolecules are summarized in this chapter. At first, electrochemical perfluorination is briefly explained, and then selective fluorination and fluorodesulfurization including recent advances in electrochemical fluorination systems such as solvent free, use of recyclable mediators, and bipolar electrolysis are mainly described. Furthermore, electrochemical fluorination using alkali metal fluoride salts and radioactive [ 18 F]fluorination are also described.

Spiers Memorial Lecture: Old but new organic electrosynthesis: history and recent remarkable developments

“…containing uoride ions to provide mostly mono-and/or diuorinated products. 96 (a) Electrochemical uorination of heteroatom and heterocyclic compounds. 97,98 In the 1990, the author's group and Laurent's group independently achieved anodic a-uorination of organosulfur compounds such as a-(phenylthio)acetate in Et 3 N-3HF/MeCN (Scheme 25: Y = Ph, R = COOEt).…”