Electrochemical determination of resveratrol in dietary supplements at a boron-doped diamond electrode in the presence of hexadecyltrimethylammonium bromide using square-wave adsorptive stripping voltammetry

Abstract

A sensitive electroanalytical methodology for the determination of resveratrol is presented for the first time using adsorptive stripping voltammetry at a bare boron-doped diamond (BDD) electrode. In cyclic voltammetry, resveratrol shows one irreversible and an adsorption-controlled oxidation peak at a BDD electrode. The voltammetric results indicated that in the presence of hexadecyl trimethyl ammonium bromide, the BDD electrode remarkably enhanced the oxidation of resveratrol, which leads to an improvement in the peak current with a shift of the peak potential to more positive values. Using the square-wave stripping mode, the compound yielded a well-defined voltammetric response in 0.1 M nitric acid solution containing 100 ?mol L-1 hexadecyl trimethyl ammonium bromide at 0.74 V (vs. Ag/AgCl), after 60 s accumulation at the open-circuit condition. A linear calibration graph was obtained in the concentration range 0.025 to 60.0 ?g mL-1, with a detection limit of 0.0063 ?g mL-1. The applicability of the proposed method was verified by analysis of resveratrol in commercial dietary supplements.

Dietary supplement mislabelling: case study on selected slimming products by developing a green isocratic HPLC method for their quality control

“…However, the trans- form is more sterically stable, abundant and biologically active 4 . As per our literature review, trans-Resveratrol was assayed in supplement products using several techniques including reversed phase high performance liquid chromatography with UV and fluorescence detection 5 – 8 , fused core column chromatography with UV detection 9 , high performance thin layer chromatography 10 , capillary electrophoresis with UV detection 11 and electrochemical detection 12 , constant wavelength synchronous spectrofluorimetry 7 and square wave 13 , 14 and differential pulse voltammetry 15 , 16 .…”

Analytical Applications of Electrochemically Pretreated Boron‐Doped Diamond Electrodes

“…The effect of surfactants on the electrochemical process of analytes on BDDEs has been fruitfully explored along with electrochemical pretreatments, mostly by Yardim and collaborators, but also by others . Yardim et al .…”

Electrochemical Determination of Flavonoid Fisetin in Commercial Dietary Supplements Using a Boron‐Doped Diamond Electrode

“…[25,[27][28][29][30] Our research group has conducted much research using the BDD electrode in the electrochemical analysis of drugs [31][32][33][34] and some polyphenolic compounds. [35,36] This paper is the first study to elucidate the electrochemical oxidation behavior of the flavonoid FST using BDD electrode surface. The first step of the method is to optimize the electrode pretreatment procedure by applying different pretreatment steps in the anodic, cathodic, and anodic followed cathodic directions to the commercial BDD electrode (the obtained electrodes were labeled as APT-BDD, CPT-BDD, and APT/CPT BDD, respectively).…”

“…On the other hand, the analytical performance of this electrode may vary depending on the boron doping level, [26] surface morphology and presence of impurities, surface tip, and applied anodic or cathodic pretreatment steps [25,27–30] . Our research group has conducted much research using the BDD electrode in the electrochemical analysis of drugs [31–34] and some polyphenolic compounds [35,36] …”