Electrochemical Determination of Neomycin and Norfloxacin at a Novel Polymer Nanocomposite Electrode in Aqueous Solution

Hamnca, Siyabulela; Phelane, Lisebo; Iwuoha, Emmanuel I.; Baker, Priscilla

doi:10.1080/00032719.2016.1261876

Cited by 29 publications

(10 citation statements)

References 21 publications

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“…After the PMDA mixture was added dropwise to the ODA mixture, the solution was stirred for 24 hours. The resulting yellowish precipitate was filtered through a membrane under suction and dried at room temperature, to produce a yield of 2,85 g of PAA as a dry white powder [11,18].…”

Section: Synthesis Of Polyamic Acidmentioning

confidence: 99%

Voltammetric and Impedimetric Detection of Norfloxacin at Co Nanoparticle Modified Polymer Composite Electrodes

2020

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The measurement of antibiotics in environmental water systems is increasingly becoming a top priority for global environmental watchdog organisations, as the looming threat of emerging contaminants moves to centre stage. A novel chemical sensor based on polyamic acid (PAA) semiconducting polymer and cobalt nanoparticles (CoNP) was developed and used to demonstrate proof of concept evidence for measurement of norfloxacin at trace concentrations in aqueous systems. Polyamic acid and cobalt nanoparticles were both chemically synthesised and characterised using Fourier transform infrared spectroscopy, transmission electron microscopy, cyclic voltammetry and small angle x-ray scattering. The polyamic acid and cobalt nanoparticles were electrodeposited onto screen printed carbon electrodes to produce novel composite sensors (SPCE/PAA/CoNP). The polymer composite chemical sensors were applied to the detection of norfloxacin in the micromolar concentration using square wave voltammetry, with a sensitivity of 18.0 � 6.59 μA/mM, calculated from the slope of the calibration curve and a limit of detection (LOD) of 0.979 � 0.419 mM, with LOD = 3.3(Sy/S). The SPCE/PAA/ CoNP sensor response to norfloxacin as measured by electrochemical impedance spectroscopy, yielded a sensitivity of 17.6 � 8.72 Ω/mM as and a limit of detection (LOD) of 0.228 � 0.0935 mM.

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Section: Synthesis Of Polyamic Acidmentioning

confidence: 99%

Voltammetric and Impedimetric Detection of Norfloxacin at Co Nanoparticle Modified Polymer Composite Electrodes

2020

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“…Meanwhile, they will retain appropriate stability. Literature survey revealed few non-biological electrochemistry-based sensors for the determination of neomycin (NEO) [36,37], gatifloxacin (GAT) [38][39][40] and sulfathiazole sodium (STNa) [41]. The aim of this study was to enhance the sensitivity of non-biologically based electrochemical methods for the three drugs by introducing surface-modified magnetic nanoparticles into the electrode inner solution.…”

Section: Introductionmentioning

confidence: 99%

Enhancing electrode sensitivity for detection of antibiotic contamination in water using functionalized magnetic nanoparticles

Farouk

Niessen²

2020

SN Appl. Sci.

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Portable electrochemical sensors for the detection of antibiotic (AB) contamination are gaining interest as point of care devices and as in-field analytical sensors. In that respect, the low cost and high sensitivity of the sensors is a major benefit. In this study, a low-cost indicator electrode was designed against neomycin (NEO), gatifloxacin (GAT) and sulfathiazole sodium (STNa) as examples of ABs with high probability of contaminating animal feed/water. Ionophore functionalized magnetic nanoparticles were incorporated into the electrode structure to enhance its performance. The detector was able to discriminate (within 10 s) AB clean from AB contaminated water in ranges of 10 −3-10 −8 M, of 10 −2-10 −8 M, and of 10 −2-10 −13 M for NEO, GAT and STNa, respectively. The developed electrodes can be fabricated at low cost; with promising fast and high sensitivity for the detection of AB contamination in water.

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“…12,13 Among these methods, the electrochemical method with the advantage of simplicity, a fast response, high sensitivity and low cost has attracted more and more attentions. [14][15][16] Therefore, the electrochemical method is promising for NF analysis in complex matrices, especially for the biological samples. However, the detection of NF based on electrochemical methods is still very rare, and some novel electrochemical techniques are still needed to be developed.…”

Section: Introductionmentioning

confidence: 99%

“…Electrochemical sensors including a carbon nanotubes (CNTs) modified electrode, 17 enzymatic rotating biosensor, 18 electrochemical immunosensor, 15 a molecularly imprinted sensor 19 and nanocomposites modified electrode have been introduced to improve the sensitivity and selectivity of NF. 12,16 In addition, cyclodextrins as one kind of selective molecular recognition elements have also been successfully used as modifiers for chemically modified electrodes to detect NF. 20 Compared to cyclodextrin, calix[n]arene generally composed of alternating phenols and methylene groups is another major class of host molecules and it has a hydrophobic and electron-rich cavity, which is well suited for complex formation.…”

Section: Introductionmentioning

confidence: 99%

Determination of Norfloxacin Using a Tetraoxocalix[2]arene[2]-triazine Covalently Functionalized Multi-walled Carbon Nanotubes Modified Electrode

Dang

Chen

et al. 2019

ANAL. SCI.

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This paper presents a sensitive voltametric procedure for the determination of norfloxacin (NF) by a tetraoxocalix[2]arene[2]triazine (TOCT) covalently functionalized multi-walled carbon nanotubes (MWCNTs) modified electrode. The electrochemical sensing of NF was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Through a combination of the excellent selective recognition of TOCT and the outstanding electronic properties of MWCNTs, this electrochemical sensor shows excellent sensitivity and high selectivity for an electrochemical detection of NF. The stripping response is highly linear (R = 0.996) over the NF concentration range of 0.5-8.0 μM with the LOD of 0.1 μM. The fabricated sensors were successfully applied for quantitative detection of NF in pharmaceutical formulations and human urine samples. A high anti-interference ability to common interferences and satisfactory results were obtained. This is expected to play a huge potential in the real-time monitoring of NF in clinical applications.

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Electrochemical Determination of Neomycin and Norfloxacin at a Novel Polymer Nanocomposite Electrode in Aqueous Solution

Cited by 29 publications

References 21 publications

Voltammetric and Impedimetric Detection of Norfloxacin at Co Nanoparticle Modified Polymer Composite Electrodes

Voltammetric and Impedimetric Detection of Norfloxacin at Co Nanoparticle Modified Polymer Composite Electrodes

Enhancing electrode sensitivity for detection of antibiotic contamination in water using functionalized magnetic nanoparticles

Determination of Norfloxacin Using a Tetraoxocalix[2]arene[2]-triazine Covalently Functionalized Multi-walled Carbon Nanotubes Modified Electrode

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