Electrochemical determination of insulin at CuNPs/chitosan-MWCNTs and CoNPs/chitosan-MWCNTs modified screen printed carbon electrodes

Determination of chloropropanol with an imprinted electrochemical sensor based on multi-walled carbon nanotubes/metal–organic framework composites

“…23 Compared with conventional porous inorganic materials, synthesis conditions of MOF are more moderate and their structures are more viable for modication. 24 Multi-walled carbon nanotubes (MWCNT) 25,26 feature relatively good conductivity and large specic area. They can increase sensitivity for electrochemical sensors and provide more reaction sites for surface of electrodes.…”

Zn Nanoparticles Modified Screen Printed Carbon Electrode as a Promising Sensor for Insulin Determination

“…ZnNPs/chitosan‐MWCNTs/SPCE was prepared to study electrocatalytic activity of ZnNPs towards glucose oxidation. As was mentioned in our previous articles [24, 36] MWCNTs were used because of rapid enlargement of surface area of working electrode and the role of chitosan was to stabilize the nanoparticles at the electrode surface [35]. Prepared ZnNPs/chitosan‐MWCNTs/SPCE with the deposition time of Zn t =45 s disposed of the lower LOD (0.23 μM), sufficient linear concentration range (0.5 μM to 5 μM) included the value of normal insulin concentration in blood (1.86 μM) and high sensitivity (0.19 mA/μM) in comparison to other nanomodified electrodes summarized in Table 1.…”

“…According to these results, the SPCE45 shows the best electrocatalytic activity towards insulin oxidation. In general, insulin oxidation on electrodes modified by transition metal nanoparticles such as nickel or copper occurs due to formation of high-valent catalytically active hydroxyoxides such as NiOOH in alkaline pH [35,36,37]. Nevertheless, such redox catalysis is not possible in the case of zinc, forming only a divalent cation.…”

Recent Advances in Electrochemical Sensors for the Detection of Biomolecules and Whole Cells

“…One example is the modified screen-printed carbon electrode (SPCE) with cobalt nanoparticles (CoNPs) with chitosan and multi walled carbon nanotubes (MWCNTs) (CoNPs/chitosan-MWCNTs/SPCE) that can successfully detect insulin with concentrations down to 25 nM. This finding could confirm the advantages of an electrochemical detection system [ 111 ]. This section describes several current sensors for hormone detection that may contribute to the development of electrochemical-based hormone sensors.…”