Electrochemical detection of uric acid and ascorbic acid using r-GO/NPs based sensors

Mazzara, Francesca; Patella, Bernardo; Aiello, Giuseppe; O’Riordan, Alan; Torino, Claudia; Vilasi, Antonio; Inguanta, Rosalinda

doi:10.1016/j.electacta.2021.138652

Cited by 137 publications

(54 citation statements)

References 65 publications

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“…To improve the sensor performance, electrodes were also modified by electrochemical deposition of reduced graphene oxide (rGO). In fact, as reported in our previous works, the excellent electrocatalytic properties of rGO ensure the increase in the sensitivity of electrochemical sensors [56,62]. In particular, we developed a simple process divided into two very short stages (first stage: deposition of rGO; second stage: deposition of PANI), which allows obtaining a double-layer electrode quickly and easily.…”

Section: Introductionmentioning

confidence: 89%

PANI-Based Wearable Electrochemical Sensor for pH Sweat Monitoring

et al. 2021

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Nowadays, we are assisting in the exceptional growth in research relating to the development of wearable devices for sweat analysis. Sweat is a biofluid that contains useful health information and allows a non-invasive, continuous and comfortable collection. For this reason, it is an excellent biofluid for the detection of different analytes. In this work, electrochemical sensors based on polyaniline thin films deposited on the flexible substrate polyethylene terephthalate coated with indium tin oxide were studied. Polyaniline thin films were abstained by the potentiostatic deposition technique, applying a potential of +2 V vs. SCE for 90 s. To improve the sensor performance, the electronic substrate was modified with reduced graphene oxide, obtained at a constant potential of −0.8 V vs. SCE for 200 s, and then polyaniline thin films were electrodeposited on top of the as-deposited substrate. All samples were characterized by XRD, SEM, EDS, static contact angle and FT-IR/ATR analysis to correlate the physical-chemical features with the performance of the sensors. The obtained electrodes were tested as pH sensors in the range from 2 to 8, showing good behavior, with a sensitivity of 62.3 mV/pH, very close to a Nernstian response, and a reproducibility of 3.8%. Interference tests, in the presence of competing ions, aimed to verify the selectivity, were also performed. Finally, a real sweat sample was collected, and the sweat pH was quantified with both the proposed sensor and a commercial pH meter, showing an excellent concordance.

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Section: Introductionmentioning

confidence: 89%

PANI-Based Wearable Electrochemical Sensor for pH Sweat Monitoring

et al. 2021

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“…Samples were characterized by means of scanning electron microscopy (SEM, FEG-ESEM, FEI QUANTA 200, OR, USA), energy dispersive spectroscopy (EDS, EDAX, Ametek, PA, USA), X-ray diffraction (XRD, RIGA, D-MAX 25,600 HK, Tokyo, Japan) and Raman spectroscopy (Renishaw, inVia Raman Microscope, UK). Characterization methods have been detailed in our previous reports [97][98][99][100][101][102].…”

Section: Fabrication Of Zno-nrs/rgomentioning

confidence: 99%

Electrochemical Synthesis of Zinc Oxide Nanostructures on Flexible Substrate and Application as an Electrochemical Immunoglobulin-G Immunosensor

et al. 2022

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Immunoglobulin G (IgG), a type of antibody, represents approximately 75% of serum antibodies in humans, and is the most common type of antibody found in blood circulation. Consequently, the development of simple, fast and reliable systems for IgG detection, which can be achieved using electrochemical sandwich-type immunosensors, is of considerable interest. In this study we have developed an immunosensor for human (H)-IgG using an inexpensive and very simple fabrication method based on ZnO nanorods (NRs) obtained through the electrodeposition of ZnO. The ZnO NRs were treated by electrodepositing a layer of reduced graphene oxide (rGO) to ensure an easy immobilization of the antibodies. On Indium Tin Oxide supported on Polyethylene Terephthalate/ZnO NRs/rGO substrate, the sandwich configuration of the immunosensor was built through different incubation steps, which were all optimized. The immunosensor is electrochemically active thanks to the presence of gold nanoparticles tagging the secondary antibody. The immunosensor was used to measure the current density of the hydrogen development reaction which is indirectly linked to the concentration of H-IgG. In this way the calibration curve was constructed obtaining a logarithmic linear range of 10–1000 ng/mL with a detection limit of few ng/mL and good sensitivity.

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“…38,91 Most of these sensors are designed to monitor changes in electrical signals caused by redox reactions, and the concentrations of the corresponding molecules can be obtained based on electrical signals. 92,93…”

Section: Glucose Lactate and Uric Acid Sensorsmentioning

confidence: 99%