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2014
DOI: 10.1007/s40097-014-0102-5
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Electrochemical detection of l-serine and l-phenylalanine at bamboo charcoal–carbon nanosphere electrode

Abstract: A carbon nanosphere electrode (CN) has been fabricated for the electrochemical detection of L-serine and L-phenylalanine. Electrochemical behavior of amino acids was investigated using cyclic voltammetry, differential pulse voltammetry, square wave voltammetry and linear sweep voltammetry. In optimal conditions, the peak current of both amino acids on the CN electrode was found to enhance greatly. A sensitive oxidation peak at 0.085 V was observed in the determination of L-serine and 0.06 V for L-phenylalanine… Show more

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Cited by 21 publications
(5 citation statements)
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“…The linear range for L -serine detection was found to be from 0.20 to 6.54 μM, with a detection limit (LOD) of 0.10 μM (signal/noise = 3) and a sensitivity of 0.33 μA μM –1 . In Table , some of the analytical characteristics obtained in this work are compared with other methods previously reported for L -serine sensing. , This method is easy to operate, simple, and convenient, suggesting a comparatively lower LOD for L -serine.…”
Section: Results and Discussionmentioning
confidence: 90%
“…The linear range for L -serine detection was found to be from 0.20 to 6.54 μM, with a detection limit (LOD) of 0.10 μM (signal/noise = 3) and a sensitivity of 0.33 μA μM –1 . In Table , some of the analytical characteristics obtained in this work are compared with other methods previously reported for L -serine sensing. , This method is easy to operate, simple, and convenient, suggesting a comparatively lower LOD for L -serine.…”
Section: Results and Discussionmentioning
confidence: 90%
“…The excessive buildup of Phe will lead to brain damage and mental retardation. , Accordingly, a simple, rapid, and highly sensitive monitoring system for detecting Phe is vital for disease diagnosis. Several detection approaches have been developed to quantify amino acids in biological fluids, including aptasensor, chemiluminescence, enzymatic colorimetric sensor, electrochemical sensor, Laser-induced fluorescence, surface plasmon resonance (SPR) sensor, and whole-cell biosensor. However, most of these methods require expensive equipment and skilled operation experience, making amino acid quantification assays and protocols more complicated. The comparative studies [method, linearity range, and limit of detection (LOD)] on the determination of Phe in the literature are given in Table .…”
Section: Introductionmentioning
confidence: 99%
“…Voltammetry is a technique utilized for the analysis of compounds that undergo oxidation or reduction. In the voltammetry methods normally using electrodes such as glassy carbon electrodes (GCE), Carbon paste electrodes (CPE), screen printed electrodes (SPE), along with some modifiers [16][17][18][19][20][21][22]. Different modifiers will show different electrochemical activities [23][24][25][26][27][28].…”
Section: Introductionmentioning
confidence: 99%