Electrochemical detection methods in capillary electrophoresis and applications to inorganic species

Kappes, Thomas; Hauser, Peter C.

doi:10.1016/s0021-9673(98)00685-2

Cited by 62 publications

(39 citation statements)

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“…Kappes and Hauser [21] have reviewed the potentiometric, amperometric and conductometric detection techniques in CE. Zemann [22] has described conductivity detection in conventional capillaries in general, which includes a discussion on CCD.…”

Section: Introductionmentioning

confidence: 99%

Contactless Conductivity Detection in Capillary Electrophoresis: A Review

2004

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The popularity of contactless conductivity detection in capillary electrophoresis has been growing steadily over the last few years. Improvements have been made in the design of the detector in order to facilitate its handling, to allow easy incorporation into available instruments or to achieve higher sensitivity. The understanding of its fundamental working principles has been advanced and the detection approach has also been transferred to lab-on-chip devices. The range of applications has been extended greatly from the initial work on small inorganic ions to include organic species and biomolecules. Concurrent determination of cations and anions by dual injection from opposite ends has been demonstrated as well as sample introduction by using flow-injection systems for easy automation of the process.

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Section: Introductionmentioning

confidence: 99%

Contactless Conductivity Detection in Capillary Electrophoresis: A Review

2004

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“…1 in [11]), efficiencies recalculated at 1/10 peak height [12] are only in the range of approximately 10 000±15 000 theoretical plates. Although the peak tailing has often been attributed to the logarithmic response characteristic of potentiometric detection which overemphasizes low concentrations [1,11], the level of tailing observed in these reports suggests that other problems with the detection system also contributed to peak tailing.…”

Section: Introductionmentioning

confidence: 87%

“…Clearly, design of a complete end-capillary electrochemical detection system is a challenging task, as reflected in a number of papers on electrochemical and mainly amperometric detection [1,2,23]. The first step was to decide on the most desirable detection geometry.…”

Section: The Approach Taken and Preliminary Investigationsmentioning

confidence: 99%

“…Potentiometric detection is an electrochemical detection mode which can be used in capillary electrophoresis (CE), complementing the more popular conductometric and amperometric detection modes [1,2]. Potentiometry was one of the first detection methods reported for CE when, in 1974, Virtanen [3] used changes in the potential of an Ag/AgCl-coated Pt wire to detect small inorganic ions separated with a 200 mm capillary.…”

Section: Introductionmentioning

confidence: 99%

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Capillary electrophoresis with end-capillary potentiometric detection using a copper electrode

et al. 1999

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“…When an electrical field is applied between the two ends of a capillary and a sample is introduced at one end, analytes are separated as they migrate towards the other end under the influence of the electrical field. These separated analytes are detected near the outlet by methods such as optical or electrochemical techniques (Polesello and Valsecchi 1999;Guijt et al 2004;Kappes and Hauser 1999;Hauser 2004, 2009;Kuhn and Hoffstetter-Kuhn 1993;Marzilli et al 1997;Tanyanyiwa et al 2002;Zemann et al 1998). The signal from a detector is digitised and typically presented in the form of voltage versus time, i.e.…”

Section: Introductionmentioning

confidence: 99%