Electrochemical bromocyclization enables 3,5-diversification of heterocyclic indolines

Ren, Hai; Wang, Rui-An; Shi, Jun; Song, Jun-Rong; Wu, Wei; Chi, Qin; Zhang, Ni

doi:10.1039/d3ob00985h

Org. Biomol. Chem.

2023

DOI: 10.1039/d3ob00985h

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Electrochemical bromocyclization enables 3,5-diversification of heterocyclic indolines

Hai Ren,

Rui-An Wang,

Jun Shi

et al.

Abstract: We report a protonic-acid-promoted electrosynthetic strategy for the dearomative dibromocyclization of tryptamine/tryptophol derivatives for the convenient late-stage 3,5-diversification of heterocyclic indolines.

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2024

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Synthesis of indolyl pyrroloindolines via a cascade arylation/cyclization of indole acetamides with 3-substituted indoles

Zhang,

Han,

Zhang

et al. 2024

Org. Chem. Front.

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Synthesis of indolyl pyrroloindolines via a cascade arylation/cyclization of indole acetamides with 3-substituted indoles

Zhang,

Han,

Zhang

et al. 2024

Org. Chem. Front.

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Electrochemical bromocyclization enables 3,5-diversification of heterocyclic indolines

Abstract: We report a protonic-acid-promoted electrosynthetic strategy for the dearomative dibromocyclization of tryptamine/tryptophol derivatives for the convenient late-stage 3,5-diversification of heterocyclic indolines.

Cited by 1 publication

References 46 publications

Synthesis of indolyl pyrroloindolines via a cascade arylation/cyclization of indole acetamides with 3-substituted indoles

Synthesis of indolyl pyrroloindolines via a cascade arylation/cyclization of indole acetamides with 3-substituted indoles

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