“…In this sense, electrochemical assays are promising tools: suitable for fast analyses, based on inexpensive instrumentation and with simple operation protocols (Prieto-Simón et al 2008). Additionally, studies propose the use of chemically modified electrodes (CMEs) as a simple electrochemical approach to sense ROS and radical scavengers, with DNA, selfassembled monolayers of thiols, polyphenol films, and conducting polymers (CPs) (Scholz et al 2007, Liu et al 2005, Mello et al 2006, Hilgemann et al 2010, Wu et al 2012, Gualandi and Tonelli 2013, Gualandi et al 2014 as electrode modifiers. The ROS may attack the CME and the extent of the modifier destruction can be evaluated directly (in this case, when an electroactive layer is monitored) or using an electrochemical probe in solution (when a non-electroactive layer is used).…”