Electrochemical antioxidant screening and evaluation based on guanine and chitosan immobilized MoS2 nanosheet modified glassy carbon electrode (guanine/CS/MoS2/GCE)

Tang, Ping; Tang, Xiaosheng; Mei, Shuqi; Fei, Junjie; Liu, Liangliang; Ren, Lixia

doi:10.1515/chem-2020-0003

Cited by 5 publications

(2 citation statements)

References 28 publications

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“…Quercetin, fisetin, and catechin were measured and found to be 45.82%, 34.39%, and 16.99%, respectively. Ascorbic acid is a comparator antioxidant; its capacity value was determined to be 51.84% [118].…”

Section: Dna-based-biosensorsmentioning

confidence: 99%

Antioxidant Determining Using Electrochemical Method

Sukma,

Iswantini,

Nurhidayat

et al. 2023

Chemistry

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Antioxidants are very beneficial for health as they protect the body from the effects of free radicals on various degenerative diseases caused by food contamination, air pollution, sunlight, etc. In general, methods for measuring the capacity of antioxidants generally use accurate methods such as spectrophotometry and chromatography. Still, this takes time, accurate sample preparation, and must be performed in a laboratory with particular expertise. Therefore, a new, more practical method needs to be developed for determining antioxidants, namely the electrochemical method. The electrochemical method is a promising method to develop because it comes with several advantages, including high sensitivity and fast response. The electrochemical method discussed in this article reviews sensors, biosensors, and nanosensors. This paper comprehensively analyzes contemporary developments in electrochemical biosensor techniques and antioxidant evaluation methodologies. The discussion centers on utilizing multiple biosensors. Electrochemical biosensors have been determined to be prevalent in analyzing food quality, assessing active factor functionality, and screening practical components. The present study outlines the difficulties linked with electrochemical bio-sensor technology and provides insights into the potential avenues for future research in this domain.

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Section: Dna-based-biosensorsmentioning

confidence: 99%

Antioxidant Determining Using Electrochemical Method

Sukma,

Iswantini,

Nurhidayat

et al. 2023

Chemistry

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“…The antioxidant capacity assay was measured as our previous report with some modifications [25]. First, a certain concentration of test sample was mixed with freshly prepared Fe 2+ -EDTA solution in phosphate buffer saline (PBS, 50 mmol L −1 , pH 3.5).…”

Section: Electrochemical Determination Of Antioxidant Capacitymentioning

confidence: 99%

Electrochemical evaluation of the antioxidant capacity of natural compounds on glassy carbon electrode modified with guanine-, polythionine-, and nitrogen-doped graphene

You

Xiao

et al. 2020

Open Chemistry

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An electrochemical sensor based on guanine-, polythionine-, and nitrogen-doped graphene modified glassy carbon electrode (G/PTH/NG/GCE) was fabricated and applied for antioxidant capacity evaluation of natural compounds and complexes in electrochemical method since natural sources of active compounds exhibited various antioxidant activities. When the antioxidants existed in the system, the generated hydroxyl radicals were scavenged and the damage to guanine immobilized on the electrode was reduced less resulting in the oxidation peak current increased in square wave voltammetry. After the modifications of polythionine- and nitrogen-doped graphene, the oxidation peak current was improved. The effects of pH, incubation time, and concentrations of guanine and Fe2+ ions on the performances of the electrode were investigated and optimized. The G/PTH/NG/GCE showed good linearity, reproducibility, and storage stability for antioxidant capacity evaluation of ascorbic acid at the optimum conditions. The antioxidant capacities of three flavonoids and three plant extracts were measured using the G/PTH/NG/GCE and DPPH methods. Myricetin showed the highest antioxidant capacity in both electrochemical and DPPH methods. The proposed G/PTH/NG/GCE exhibited easy fabrication procedure, rapid detection time, and low cost for the detection of antioxidant activity for various kinds of samples.

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State‐of‐the‐art electrochemistry for the assessment of oxidative stress and integral antioxidant activity of biological environments

Брайнина

Shpigun

2022

Electrochemical Science Adv

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The present review focuses on the interplay between electrochemistry and life, events on the border of electrochemistry‐biology‐life science, electrochemistry as the basis, and the information source on oxidative stress (OS) or Red/Ox state of biological systems and food to be investigated. Electroanalytical chemistry provides rapid, relatively simple, and sensitive approaches to assess the redox characteristics and antioxidant activity of biologically active compounds in various samples.OS is a relatively new physiological response concept, recognized in medicine and biology in the last three decades. This phenomenon is caused by an imbalance between (pro)oxidants and antioxidants in living organisms and it is related to the fundamental redox reactions that underlie health signaling and life processes in general. OS can contribute to many pathological conditions and diseases. In particular, it is recognized that a highly contagious infectious disease, coronavirus disease 2019, is associated with an inflammation process related to OS‐induced cellular changes. Recent years have shown a marked increase in electrochemical studies of OS and quantitation of its reductant‐oxidant markers (signaling agents), such as reactive oxygen species and antioxidants.The goal of this overview is to cover the brief scope of modern electrochemical analysis and sensor devices for monitoring biomarkers of OS and antioxidant status of biological systems. By discussing the great potential of potentiometric and voltammetric methods for human health assessment, it is hoped to bridge between recent electrochemical research and medical diagnostic treatment in the 21st century.

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Electrochemical antioxidant screening and evaluation based on guanine and chitosan immobilized MoS2 nanosheet modified glassy carbon electrode (guanine/CS/MoS2/GCE)

Cited by 5 publications

References 28 publications

Antioxidant Determining Using Electrochemical Method

Antioxidant Determining Using Electrochemical Method

Electrochemical evaluation of the antioxidant capacity of natural compounds on glassy carbon electrode modified with guanine-, polythionine-, and nitrogen-doped graphene

State‐of‐the‐art electrochemistry for the assessment of oxidative stress and integral antioxidant activity of biological environments

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