Electrocatalytic Quantification of Pantaprazole

Abstract

A polyaniline-zinc oxide-modified glassy carbon electrode (PANI-ZnO/GCE) has been developed for the determination of pantaprazole. The morphology of fabricated PANI-ZnO/GCE was characterized by scanning electron microscopy. The electrochemical behavior of pantaprazole on PANI-ZnO/GCE was investigated using square-wave cathodic adsorptive stripping voltammetry (SWCAdSV). Results showed that PANI-ZnO/GCE modified sensor exhibited excellent electrocatalytic activity to pantaprazole with a detection limit of 45.59 ng/mL, a reproducibility of 2.07% relative standard deviation, and a recovery from 99.76% to 99.81%. The ease of fabrication, high electroactive surface area and excellent electrochemical performance are the promising feature of the sensor.

Green Electroanalytical Method for Fast Measurement of Xanthine Oxidase Inhibitor Febuxostat

“…The wide linear range obtained at the BDDE is comparable to those found using modified electrodes. 26,27 In addition, the BDDE has a wider linear range than the previously reported toxic mercury electrode. 25 Although the LOD value achieved with the BDDE is in a higher concentration, the working range of the presented method is satisfactory for quantification of FBX in pharmaceutical products.…”

“…In this method, methanol was used as the toxic solvent. Very recently, the same authors 27 developed a graphene/zinc oxide nanoflowers modified glassy carbon electrode for determination of FBX. The method is also based on reduction of the drug molecule at very negative potential of -1.65 V versus Ag/AgCl in background electrolyte with added toxic methanol.…”