Electrocardiographic stress tolerance tests

Simonson, Ernst

doi:10.1016/0033-0620(70)90003-4

Cited by 42 publications

(5 citation statements)

References 76 publications

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“…As this effect was often not reproducible, they considered that it might be due to psychic causes. Other workers have confirmed that the T wave is reduced in normal subjects in hypoxemia (12,16,21). This T reduction has been observed in normal subjects even at an arterial saturation of between 70 and 80 % (17).…”

supporting

confidence: 52%

Calibrated Hypoxemia Test in Normal Subjects and Coronary Patients

Broch

1972

Journal of Internal Medicine

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In 13 patients with angina pectoris and 5 normal subjects hypoxemia tests have been carried out, with continual registration of the arterial O2 saturation and ECG. A gradual depression of the T wave was found during hypoxemia in most cases. There was no difference in the pattern found in normal subjects and coronary patients. The S‐T depression during hypoxemia was not found in the normal subjects. In 6 patients with angina pectoris the S‐T change occurred in the course of 3–4 min, at somewhat differing degrees of saturation, depending on the degree of angina pectoris. When the mask was removed, the arterial saturation rose rapidly in the course of approximately 30–40 sec. In most cases the ECG was normalized before saturation was complete. In a few cases the ECG changes persisted for some minutes before full saturation occurred. On repeated tests in the same patient the S‐T changes occurred within the same saturation range. The deviation was, on the average, 2.4%. On administration of nitroglycerine the tolerance of the myocardium to hypoxemia increased, the S‐T depression occurring only at considerably lower degrees of saturation and normalization occurring more rapidly. It therefore seems that a calibrated hypoxemia test with continuous O2 registration is capable of giving a standardized and reproducible registration of the degree of coronary insufficiency. This test will also permit the registration of the effect of medication on coronary insufficiency.

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supporting

confidence: 52%

Calibrated Hypoxemia Test in Normal Subjects and Coronary Patients

Broch

1972

Journal of Internal Medicine

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“…This data base was CONTROL subsequently used to calculate the median (50th percentile) and the 10th and 90th percentile limits for each stated measurement at selected treadmill protocol times. We chose this nonparametric approach in presenting our data because the use of percentiles 1) does not require an assumption of a normal distribution of the population reported, and 2) this type of presentation is easily understood by most people. Our specific use of the 10th and 90th percentiles was an arbitrary choice and provides relatively conservative limits for the response of healthy men to treadmill exercise.…”

Section: Methodsmentioning

confidence: 99%

The response of healthy men to treadmill exercise.

Wolthuis¹,

Froelicher²,

Fischer³

et al. 1977

Circulation

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SUMMARY Heart rates, blood pressures, and functional responses to submaximal, maximal and postexertional treadmill testing are presented for a group of 704 healthy, asymptomatic aircrewmen referred to the USAF School of Aerospace Medicine. The THE INTERPRETATION OF ELECTROCARDIO-GRAPHIC CHANGES in response to exercise testing is of established value in the early detection, diagnosis, and subsequent management of coronary atherosclerotic heart disease (CAD).'`The major emphasis placed on interpretation of the exercise electrocardiogram (ECG) has, however, tended to de-emphasize the value and significance of other commonly acquired exercise performance measurements (i.e., heart rate, blood pressure, and functional capacity). These latter measurements are currently attracting renewed attention as part of an effort to improve the overall sensitivity and specificity of exercise testing. Recent reports have suggested that maximal oxygen consumption,6 functional aerobic capacity estimated from maximal treadmill time,7 8 maximal and submaximal heart rate and blood pressure,9-" and the maximal heart rate-blood pressure product,'2 may also be useful indices for identifying the presence and/or severity of CAD in patients.The value of any measurement in providing useful diagnostic information from treadmill testing depends upon: a) the accuracy and completeness with which the measurement has been made in healthy individuals (the reference values); and b) the effectiveness with which certain limits of the measurement (discriminant values) separate healthy individuals from those with known health disorders.'3 Previously published studies have reported reference values based on the response of healthy individuals to treadmill testing. Unfortunately, a majority of these studies were based on a small sample size, and statistics based on them are less likely to provide a true estimate of population parameters than is a comparable study based on a larger number. In the remaining few studies with a larger sample size, data for both submaximal and postexertional treadmill responses are fragmentary and incomplete. Hence, the practicing clinician has not had a complete and readily available set of reference values for use with his application of treadmill exercise testing.The purpose of the present report is to establish a complete set of reference values for the response of healthy men indicated measurements are individually described by the use of percentiles. These data provide the practicing clinician with an accurate and complete description of the response of healthy men to treadmill exercise.to submaximal, maximal, and postexertional treadmill testing. In addition to diagnostic use, these reference values serve as a basis for monitoring individuals during treadmill testing to assure patient safety. Finally, this study may provide the basis for subsequent studies which seek to establish discriminant values that separate healthy individuals from those with specific health disorders. Materials and MethodsThe United States Air Forc...

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“…The exercise ECG is principally used to detect latent coronary artery disease, and its great value in predicting the increased probability of cardiac events after a positive exercise ECG has been commented on (16,50,158). It is questionable whether the large number of positive stress ECG responses in this series represents a high incidence of coronary artery disease only; other factors may be involved.…”

Section: Discussionmentioning

confidence: 94%

Coarctation of the thoracic aorta in adults: A follow-up study after surgical treatment

Ala-Kulju

1981

Scandinavian Journal of Thoracic and Cardiovascular Surgery

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Electrocardiographic stress tolerance tests

Cited by 42 publications

References 76 publications

Calibrated Hypoxemia Test in Normal Subjects and Coronary Patients

Calibrated Hypoxemia Test in Normal Subjects and Coronary Patients

The response of healthy men to treadmill exercise.

Coarctation of the thoracic aorta in adults: A follow-up study after surgical treatment

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