Electrocardiographic Changes During Oesophago-Gastro-Duodenoscopy

Abstract

We were very interested by the article of Pyörálá et al. (Electrocardiographic changes during Gastroscopy, Endoscopy 5 [1973] 186.Since we have recently completed a similar study we would like to comment on several points and briefly report our results.Continuous electrocardiographic recording on tape (Holter system 3) was performed in 52 patients undergoing a gastro-duodenoscopy. The procedure was always performed by the same investigator with a fiberscope (panendoscope ACMI). None of the patients Downloaded by: Chinese University of Hong Kong. Copyrighted material.

Effects on rabbit cardiac potentials of aprindine and indecainide, a new antiarrhythmic agent, in normoxia and hypoxia

“…(b) Depolarization ofcardiac muscle Atria Both indecainide and aprindine (at concentrations including the range observed in the plasma of treated patients (Van Durme et al, 1974)) depressed action potential amplitude (APA), MRD and conduction velocity in a dose-related manner (Table 1). There was no significant effect on resting potential.…”

“…Aprindine was introduced a decade ago as a very potent class 1 antiarrhythmic agent, reported to be superior to procainamide and quinidine in cross-over studies of patients with stable ventricular arrhythmias (Van Durme et al, 1974): it has since proved useful also in the treatment of supraventricular arrhythmias (Singh, 1981). It widened QRS and prolonged Hisventricular (H-V) conduction time in man (Kesteloot et al, 1973;Singh, 1981); in vitro it shortened the action potential duration (APD) in Purkinje fibres but caused no corresponding shortening of the effective refractory period Carmeliet & Verdonck, 1974;Steinberg & Greenspan, 1976).…”

Μεταβολες Επιλεγμενων Παραμετρων Της Καρδιακης Λειτουργιας Κατα Την Ενδοσκοπηση Του Ανωτερου Πεπτικου Συστηματος. Συγκριτικη Μελετη Καρδιοπροστατευτικων Φαρμακων (Νιφεδιπινη Και Προπρανολολη)

“…"Αλλοι συγ γραφείς σέ σύνολο 52 ασθενών διαπίστωσαν κατάσπαση του διαστήματος S-T στό 15% τών περιπτώσεων καί κοιλιακή αρρυθμία στό 25%. 219 Μέτρια ή καί αρκετά υψη λά ποσοστά έχουν επίσης παρατηρηθεί καί άπό άλλους συγγραφείς.…”