Electrocardiographic Changes during Isoflurane Anesthesia Suggesting Asymptomatic Coronary Artery Disease in Three Patients

Šprung, Juraj; Joseph, G; Murray, Kathleen; OʼHara, Jerome F.

doi:10.1097/00000542-199509000-00026

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…Whether isoflurane causes coronary steal is controversial, but its use in patients with angina is considered safe (8,9). Intraoperatively, our patient had isoflurane as low as 0.1% end-tidal without improvement of the ST segment.…”

Section: Discussionmentioning

confidence: 80%

The Resolution of ST Segment Depressions After High Right Thoracic Paravertebral Block During General Anesthesia

Ho¹,

Lim²,

Yim³

et al. 2002

Anesthesia &Amp; Analgesia

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Section: Discussionmentioning

confidence: 80%

The Resolution of ST Segment Depressions After High Right Thoracic Paravertebral Block During General Anesthesia

Ho¹,

Lim²,

Yim³

et al. 2002

Anesthesia &Amp; Analgesia

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“…The S-T segment changes occurred in all treatments during isoflurane anaesthesia. Sprung et al studied isoflurane anaesthesia and found that it induced S-T changes and ECG changes consistent with myocardial ischemia [36]. Tatekawa et al showed that maintaining the mean arterial pressure at 80 mmHg was sufficient to prevent myocardial ischemic changes in dogs [37].…”

Section: Discussionmentioning

confidence: 99%

Dexmedetomidine combined with etomidate or emulsified isoflurane for induction reduced cardiopulmonary response in dogs

2018

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To investigate the effects of etomidate, emulsified isoflurane, and their combination with dexmedetomidine on physiological parameters, electrocardiogram (ECG) results, and the quality of induction and recovery during isoflurane maintenance anaesthesia. 5 mixed-breed dogs received each of four treatments: etomidate (E group); emulsified isoflurane (EI group); both dexmedetomidine and etomidate (DE group); or both dexmedetomidine and emulsified isoflurane (DEI group). All drugs were IV injection administered for induction, followed by 1.5 MAC (minimal alveolar concentration) of isoflurane to maintain anaesthesia. Rectal temperature (RT), respiratory rate (RR), heart rate (HR), mean arterial pressure (MAP), and ECG were measured at baseline, 0, 5, 10, 20, 40, and 60 minutes after intubation. The quality of induction and recovery was evaluated for all dogs. All the anaesthetic procedures provided good conditions for induction of anaesthesia. The quality of induction and recovery in the E group was worse than other groups. The decrease of RR in the E and DE groups was stronger than that in the EI and DEI groups. The dogs in the E group had the most significant prolongation of the Q-T interval and changes in the S-T segment. Deviation and extension of the S-T segment were noted in the El group. The dogs in the DE and DEI groups had fewer changes in the ECG results than those in the E and EI groups. The addition of dexmedetomidine caused less effect on cardiopulmonary parameters and the ECG results than either etomidate or emulsified isoflurane alone. Thus, etomidate or emulsified isoflurane in combination with dexmedetomidine may be useful clinically for the induction of anaesthesia.

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Acute Coronary Vasospasm During Thoracic Spine Surgery

Krishnan

Eipe

Korula

2003

Journal of Neurosurgical Anesthesiology

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Cardiac ischemia is a well-known and serious complication during surgery. The authors describe a case of acute coronary vasospasm in a young patient undergoing thoracic laminectomy with biopsy of intramedullary tumor. The possible role of the autonomic nervous system in the causation of acute coronary vasospasm is discussed, and this is highlighted as an unusual cause of myocardial ischemia during thoracic spine surgery.

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Electrocardiographic Changes during Isoflurane Anesthesia Suggesting Asymptomatic Coronary Artery Disease in Three Patients

Cited by 4 publications

References 10 publications

The Resolution of ST Segment Depressions After High Right Thoracic Paravertebral Block During General Anesthesia

The Resolution of ST Segment Depressions After High Right Thoracic Paravertebral Block During General Anesthesia

Dexmedetomidine combined with etomidate or emulsified isoflurane for induction reduced cardiopulmonary response in dogs

Acute Coronary Vasospasm During Thoracic Spine Surgery

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