Electroacupuncture: Current strength-duration relationship for initiation of hypesthesia in man

Ishiko, Nobusada; Yamamoto, Toshikatsu; Murayama, Nobuki; Hanamori, Takamitsu

doi:10.1016/0304-3940(78)90135-0

Cited by 6 publications

(2 citation statements)

References 12 publications

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“…Acupuncture is a traditional therapeutic technique in oriental medicine, with a long history of approximately 3000 years. In the 1970s, electroacupuncture (EA), a modern version of acupuncture, began to replace manual manipulation because EA has better analgesic effects and its stimulation can be objectively quantified and controlled [ 1 ]. EA has been widely used for treating various pathologic conditions.…”

Section: Introductionmentioning

confidence: 99%

The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain

Qiu

Ding

Cui

et al. 2015

Evidence-Based Complementary and Alternative Medicine

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To investigate patterns of c-Fos and c-Jun expression induced by different frequencies of electroacupuncture (EA) in the brain, goats were stimulated by EA of 0, 2, 60, or 100 Hz at a set of “Baihui, Santai, Ergen, and Sanyangluo” points for 30 min. The pain threshold was measured using the potassium iontophoresis method. The levels of c-Fos and c-Jun were determined with Streptavidin-Biotin Complex immunohistochemistry. The results showed that the pain threshold induced by 60 Hz was 82.2% higher (P < 0.01) than that by 0, 2, or 100 Hz (6.5%, 35.2%, or 40.9%). EA induced increased c-Fos and c-Jun expression in most analgesia-related nuclei and areas in the brain. Sixty Hz EA increased more c-Fos or c-Jun expression than 2 Hz or 100 Hz EA in all the measured nuclei and areas except for the nucleus accumbens, the area septalis lateralis, the caudate nucleus, the nucleus amygdala basalis, and the locus coeruleus, in which c-Fos or c-Jun expressions induced by 60 Hz EA did not differ from those by 2 Hz or 100 Hz EA. It was suggested that 60 Hz EA activated more extensive neural circuits in goats, which may contribute to optimal analgesic effects.

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Section: Introductionmentioning

confidence: 99%

The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain

Qiu

Ding

Cui

et al. 2015

Evidence-Based Complementary and Alternative Medicine

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“…Studies indicate it not only reduces DPN symptoms but also aids in glycemic control [21][22][23][24]. EA is an extension technique based on acupuncture that combines electrical stimulation and traditional acupuncture that can be adjusted to different waveforms, frequencies, stimulation intensities and duration according to personal needs, thus improving efficacy and making it more accessible to DPN patients [25]. A previous animal experiment conducted by our research group showed that EA at 2 and 100Hz attenuated pain in type 2 diabetic neuropathic pain rats [26].…”

Section: Introductionmentioning

confidence: 99%

The efficacy and safety of electroacupuncture for diabetic peripheral neuropathy: A protocol for a systematic review and meta-analysis

Wang,

Zhang,

et al. 2024

PLoS ONE

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Background Diabetic peripheral neuropathy (DPN) is a chronic complication of diabetes mellitus, which is the most common neuropathy worldwide. Owing to the inadequacies of existing treatment methods, managing DPN remains a significant challenge. Studies suggest that electroacupuncture (EA) could potentially serve as a beneficial alternative treatment for this condition. Nevertheless, there is still inadequate proof of its therapeutic effectiveness and safety. As a result, the goal of this protocol is to methodically compile the data pertaining to the effectiveness and security of EA in the management of DPN. Methods To find appropriate randomized controlled trials (RCTs), nine reliable databases in the English and Chinese languages will be examined. RevMan5.3 will be used to combine the retrieved data and perform meta-analyses. The methodological quality of the included RCTs will be evaluated using the Cochrane Risk of Bias Assessment 2.0 tool. The Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) system will be utilized to evaluate the degree of strength and certainty of the evidence. We will also perform publication bias, sensitivity and subgroup analyses. Discussion This protocol describes the intended scope and approach for a forthcoming systematic review and meta-analysis that will inform therapeutic decision-making by offering current information on the efficacy and safety of EA in the treatment of DPN. The results of the study will help standardize strategies for EA in the treatment of DPN.

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Low-Frequency Electroacupuncture Alleviates Chronic Constrictive Injury-Induced Mechanical Allodynia by Inhibiting NR2B Upregulation in Ipsilateral Spinal Dorsal Horn in Rats

Zhao

Jiang

Shi

et al. 2018

Chin. J. Integr. Med.

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Electroacupuncture: Current strength-duration relationship for initiation of hypesthesia in man

Cited by 6 publications

References 12 publications

The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain

The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain

The efficacy and safety of electroacupuncture for diabetic peripheral neuropathy: A protocol for a systematic review and meta-analysis

Low-Frequency Electroacupuncture Alleviates Chronic Constrictive Injury-Induced Mechanical Allodynia by Inhibiting NR2B Upregulation in Ipsilateral Spinal Dorsal Horn in Rats

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