Electro-blown spinning: New insight into the effect of electric field and airflow hybridized forces on the production yield and characteristics of nanofiber membranes

Elnabawy, Eman; Sun, Dongyang; Shearer, Neil; Shyha, Islam

doi:10.1016/j.jsamd.2023.100552

Cited by 10 publications

(8 citation statements)

References 160 publications

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“…Innovative approaches have been focused on creating reliable and affordable spinning methods, and making them more scalable and easier to use. Considering this, further cutting-edge techniques for the creation of nanofibers have been presented, including solution-blown spinning, CO 2 laser supersonic drawing, airflow bubble spinning, plasma-induced synthesis, and electro-blown spinning [ 41 ].…”

Section: Trends In Embedding Ucnp’s In Nanofibermentioning

confidence: 99%

Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers

Dubey,

Chandra

2024

Biosensors

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Electrospun nanofibers possess a large surface area and a three-dimensional porous network that makes them a perfect material for embedding functional nanoparticles for diverse applications. Herein, we report the trends in embedding upconversion nanoparticles (UCNPs) in polymeric nanofibers for making an advanced miniaturized (bio)analytical device. UCNPs have the benefits of several optical properties, like near-infrared excitation, anti-Stokes emission over a wide range from UV to NIR, narrow emission bands, an extended lifespan, and photostability. The luminescence of UCNPs can be regulated using different lanthanide elements and can be used for sensing and tracking physical processes in biological systems. We foresee that a UCNP-based nanofiber sensing platform will open opportunities in developing cost-effective, miniaturized, portable and user-friendly point-of-care sensing device for monitoring (bio)analytical processes. Major challenges in developing microfluidic (bio)analytical systems based on UCNPs@nanofibers have been reviewed and presented.

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Section: Trends In Embedding Ucnp’s In Nanofibermentioning

confidence: 99%

Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers

Dubey,

Chandra

2024

Biosensors

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“…For example, Qin et al 32 observed that the addition of airflow facilitated jet emission and significantly improved nanofiber deposition on the collector electrode surface. Recently, Elnabawy et al 33 employed high voltage and compressed airflow to enhance solution jet stability, resulting in nanofiber mats with uniform distribution and extremely fine diameter. The simulation results for wind field during electrostatic spinning process using COMSOL software were presented in Figure 4b, demonstrating that introducing airflow can improve jet stability.…”

Section: Simulation Of the External Fieldassisted Electrostatic Spinn...mentioning

confidence: 99%

Artificial neural networks for the accurate prediction of the thickness of fiber membranes prepared by airflow‐assisted electrostatic spinning

Ma,

Zheng,

Zeng

et al. 2024

J of Applied Polymer Sci

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The practical application of fiber membranes prepared by electrostatic spinning requires a uniform thickness. However, the parameters involved in the spinning process are highly complex, particularly when it comes to precise control over membrane thickness. Hence, achieving a consistent and homogeneous thickness for fiber membranes has posed significant challenges thus far. To accurately predict membrane thickness during the spinning process and ensure consistent outcomes, this study employed polyvinylidene fluoride as the raw material and optimized electrostatic spinning preparation using an innovative airflow‐assisted strategy. The as‐proposed preparation strategy effectively enhances the volatilization of solvents within the jet, also promotes jet stretching through assistance from airflow, resulting in a more stable and homogeneous fiber diameter. Additionally, COMSOL simulations were utilized to provide rational explanations for these findings. By collecting multiple process parameters, including positive voltage, liquid supply speed, winding speed, and solution concentration, this study has successfully developed an artificial neural network (ANN) that exhibits reliable predictive capabilities for membrane thickness. Notably, the model demonstrates a remarkable goodness‐of‐fit with an R2 value of 0.9981. Through the integration of ANN with electrostatic spinning technology, significant advancements have been achieved in accurately predicting and controlling the uniformity of electrostatically spun polymer fiber membranes.

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“…These scaffolds are very porous and can offer optimal conditions for cell migration and proliferation in addition to favorable conditions for cell adhesion. The nanofiber scaffolds has been developed by electrospinning, 142,143 blow spinning, 144,145 centrifugal spinning 146 or combination of multiple techniques 147,148 based upon the requirements. Nanofibers reduce the inflammatory response and enhance macrophage transformation into M2 type.…”

Section: Nanotopographies and Theirmentioning

confidence: 99%

Attributes of Nanomaterials and Nanotopographies for Improved Bone Tissue Engineering and Regeneration

Karmakar,

Dey,

Alam

et al. 2023

ACS Appl. Bio Mater.

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Bone tissue engineering (BTE) is a multidisciplinary area that can solve the limitation of conventional grafting methods by developing viable and biocompatible bone replacements. The three essential components of BTE, i.e., Scaffold material and Cells and Growth factors altogether, facilitate support and guide for bone formation, differentiation of the bone tissues, and enhancement in the cellular activities and bone regeneration. However, there is a scarcity of the appropriate materials that can match the mechanical property as well as functional similarity to native tissue, considering the bone as hard tissue. In such scenarios, nanotechnology can be leveraged upon to achieve the desired aspects of BTE, and that is the key point of this review article. This review article examines the significant areas of nanotechnology research that have an impact on regeneration of bone: (a) scaffold with nanomaterials helps to enhance physicochemical interactions, biocompatibility, mechanical stability, and attachment; (b) nanoparticle-based approaches for delivering bioactive chemicals, growth factors, and genetic material. The article begins with the introduction of components and healing mechanisms of bone and the factors associated with them. The focus of this article is on the various nanotopographies that are now being used in scaffold formation, by describing how they are made, and how these nanotopographies affect the immune system and potential underlying mechanisms. The advantages of 4D bioprinting in BTE by using nanoink have also been mentioned. Additionally, we have investigated the importance of an in silico approach for finding the interaction between drugs and their related receptors, which can help to formulate suitable systems for delivery. This review emphasizes the role of nanoscale approach and how it helps to increase the efficacy of parameters of scaffold as well as drug delivery system for tissue engineering and bone regeneration.

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Electro-blown spinning: New insight into the effect of electric field and airflow hybridized forces on the production yield and characteristics of nanofiber membranes

Cited by 10 publications

References 160 publications

Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers

Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers

Artificial neural networks for the accurate prediction of the thickness of fiber membranes prepared by airflow‐assisted electrostatic spinning

Attributes of Nanomaterials and Nanotopographies for Improved Bone Tissue Engineering and Regeneration

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