Abstract:The combination of electrical stimulation (ES) and bone tissue engineering (BTE) has been successful in treatments of bone regeneration. This study evaluated the effects of ES combined with PCL + β-TCP 5% scaffolds obtained by rotary jet spinning (RJS) in the regeneration of bone defects in the calvaria of Wistar rats. We used 120 animals with induced bone defects divided into 4 groups (n = 30): (C) without treatment; (S) with PCL+ β-TCP 5% scaffold; (ES) treated with ES (10 μA/5 min); (ES + S) with PCL + β-TC… Show more
“…In a bone defect rat model with a rotary jet-spun implant, inflammatory infiltration was significantly lower following 30 d of external electrostimulation than in the control [ 169 ]. Although the underlying mechanisms remain unclear, this is thought to be related to the effect of electrostimulation on mast cells [ 170 ].…”
Section: Effects Of Electrostimulation On Osteogenesismentioning
“…In a bone defect rat model with a rotary jet-spun implant, inflammatory infiltration was significantly lower following 30 d of external electrostimulation than in the control [ 169 ]. Although the underlying mechanisms remain unclear, this is thought to be related to the effect of electrostimulation on mast cells [ 170 ].…”
Section: Effects Of Electrostimulation On Osteogenesismentioning
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