Electrical Characterization of Pork Tissue Measured by a Monopolar Injection Needle and Discrete Fourier Transform based Impedance Measurement

Abbasi, Muhammad Aitzaz; Kim, Jun-Sub; Kim, Tae-Hee; Park, Ki Deok; Cho, Sungbo

doi:10.3390/app9194049

Cited by 7 publications

(11 citation statements)

References 22 publications

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“…A parylene-coating test was conducted to check the impedance of the MNE before and after the parylene coating. We used 0.9% NaCl for the test because it has the same pH and conductivity levels as the human extracellular fluids [ 29 , 30 ]. The MNEs were immersed in a 0.9% NaCl solution, and the other side was connected to the impedance-measurement system CompactStat potentiostat from IVIUM Technologies (Eindhoven, The Netherlands).…”

Section: Methodsmentioning

confidence: 99%

Fabrication of Parylene-Coated Microneedle Array Electrode for Wearable ECG Device

Satti

Park

et al. 2020

Sensors

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Microneedle array electrodes (MNE) showed immense potential for the sensitive monitoring of the bioelectric signals by penetrating the stratum corneum with high electrical impedance. In this paper, we introduce a rigid parylene coated microneedle electrode array and portable electrocardiography (ECG) circuit for monitoring of ECG reducing the motion artifacts. The developed MNE showed stability and durability for dynamic and long-term ECG monitoring in comparison to the typical silver-silver chloride (Ag/AgCl) wet electrodes. The microneedles showed no mechanical failure under the compression force up-to 16 N, but successful penetration of skin tissue with a low insertion force of 5 N. The electrical characteristics of the fabricated MNE were characterized by impedance spectroscopy with equivalent circuit model. The designed wearable wireless ECG monitoring device with MNE proved feasibility of the ECG recording which reduces the noise of movement artifacts during dynamic behaviors.

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Section: Methodsmentioning

confidence: 99%

Fabrication of Parylene-Coated Microneedle Array Electrode for Wearable ECG Device

Satti

Park

et al. 2020

Sensors

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“…On the PC the data is averaged to get the best data. The time required is around 600 ms. (d) Calculation the value of 'mag (dB)' using Equation (15) and the value of 'θ (degree)' using Equation (16). Calculation the value of complex impedance magnitude, real part and imaginary part of complex impedance using Equation (17).…”

Section: Prototype Of the Bis Instrumentation Systemmentioning

confidence: 99%

“…The α-dispersion (10 Hz to 10 kHz) is related to the phenomena of ionic diffusion of the cell membrane and the counterion effects, the β-dispersion (10 kHz to 100 MHz) is related to the polarization phenomenon of cell membranes, and the γ-dispersion (in GHz order) is related to the polarization of water molecules [3]. Properties of electrical impedance have been reported to understand the nature and behavior of cell [4][5][6][7][8], bacteria detection and identification [9,10], identification of beverages and food ingredients [11][12][13][14][15][16], and so on. In the medical field, BIS is used to characterizations of serum and blood [17][18][19], identification of body composition and disease [20][21][22], and to assist the process of diagnosis and functional electrical stimulation of the body [23][24][25].…”

Section: Introductionmentioning

confidence: 99%

Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots

et al. 2020

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Bioelectric impedance spectroscopy (BIS) has been widely used to study the electrical properties of biological tissue based on the characteristics of the complex electrical impedance dispersions. One of the problems in using the BIS method is the length of time required for the data acquisition process and possibly data analysis as well. In this research, a compact and work rapidly BIS instrumentation system has been developed at a low cost. It is designed to work in the frequency range of 100 Hz to 100 kHz, which is generally used in the fields of biophysics and medical physics. The BIS instrumentation system is built using several integrated modules. The modules are an AC current source to produce a selectable injection current; a data acquisition system to measure voltage, current, and phase difference rapidly and simultaneously; and software to calculate and display measurement results in the form of Bode and Nyquist plots in real time. The developed BIS system has been validated using a simple RC circuit as the sample being tested. The average time needed in the process of data acquisition and analysis until the formation of impedance dispersion curves in the form of Bode and Nyquist plots, for 54 sample frequencies, is less than one minute. The system is able to identify R and C values of the sample with a maximum error of 1.5%. In addition, some simple application examples are also presented in this paper.

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“…A monopolar needle was used to simultaneously measure the impedance and administer the drug. Electrical impedance monitoring revealed major differences between the dermis, hypodermis, and muscle tissue [23,24].…”

Section: Introductionmentioning

confidence: 99%

Real-Time Impedance Detection of Intra-Articular Space in a Porcine Model Using a Monopolar Injection Needle

Abbasi

Kim

Chinnadayyala

et al. 2020

Sensors

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Rheumatoid arthritis and osteoarthritis can be treated through specific drug injection into the intra-articular space. Several failures during drug injection attempts with conventional fluoroscopy and ultrasonography in a small area of the intra-articular space have been reported. In this work we present an innovative impedance measurement-based method/algorithm for needle tip positioning to enhance image-guided intra-articular vaccination treatment. A novel algorithm for detecting the intra-articular space in the elbow and knee joints of a live porcine model is reported. An impedance measurement system was developed for biological tissue measurement. The electrical impedance in the intra-articular space was monitored and the needle tip was examined by ultrasonography. The contrast dye was vaccinated and checked using fluoroscopy to confirm that the dye was properly inoculated in the cavity. The electrical impedance was estimated for various needle inclusion profundity levels in saline solution, which were broadly used to evaluate the proposed device for in vivo examinations. Good efficiency was observed in the impedance-based measurements using a monopolar injection needle for intra-articular therapy. To enhance the needle tip positioning for intra-articular therapy, the intended impedance measurement device with a monopolar injection needle can be used as a complement to existing modalities.

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Electrical Characterization of Pork Tissue Measured by a Monopolar Injection Needle and Discrete Fourier Transform based Impedance Measurement

Cited by 7 publications

References 22 publications

Fabrication of Parylene-Coated Microneedle Array Electrode for Wearable ECG Device

Fabrication of Parylene-Coated Microneedle Array Electrode for Wearable ECG Device

Low-Cost, Compact, and Rapid Bio-Impedance Spectrometer with Real-Time Bode and Nyquist Plots

Real-Time Impedance Detection of Intra-Articular Space in a Porcine Model Using a Monopolar Injection Needle

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