Electric field distribution predicts efficacy of accelerated intermittent theta burst stimulation for late-life depression
Davin K. Quinn,
Joel Upston,
Thomas R. Jones
et al.
Abstract:IntroductionRepetitive transcranial magnetic stimulation (rTMS) is a promising intervention for late-life depression (LLD) but may have lower rates of response and remission owing to age-related brain changes. In particular, rTMS induced electric field strength may be attenuated by cortical atrophy in the prefrontal cortex. To identify clinical characteristics and treatment parameters associated with response, we undertook a pilot study of accelerated fMRI-guided intermittent theta burst stimulation (iTBS) to … Show more
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