Elective lung resection after treatment for COVID-19 pneumonia

Sakai, Takashi; Azuma, Yoko; Aoki, Kotaro; Wakayama, Megumi; Miyoshi, Shion; Kishi, Kazuma; Tateda, Kazuhiro; Homma, Sakae; Iyoda, Akira

doi:10.1007/s11748-021-01630-4

Cited by 9 publications

(8 citation statements)

References 3 publications

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“…Therefore, we decided to perform pulmonary resection, and we expected a long survival time when the patient did well postoperatively without acute exacerbation. Sakai et al reported that organized fibrosis and inflammation might remain for a prolonged period after recovery from COVID-19, even with improved radiological findings (1). The present case had fibrotic change after COVID-19, pathologically.…”

Section: Discussionsupporting

confidence: 42%

“…The spread of COVID-19 infection increased the number of patients treated for lung cancer after COVID-19 infection. There are reports of patients who underwent pulmonary resection for lung cancer after COVID-19 infection ( 1 – 4 ). The mortality risk with surgery after COVID-19 infection is increased for up to 5–6 weeks after COVID-19 infection ( 7 ).…”

Section: Discussionmentioning

confidence: 99%

“…Sakai et al reported that organized fibrosis and inflammation might remain for a prolonged period after recovery from COVID-19, even with improved radiological findings ( 1 ). The present case had fibrotic change after COVID-19, pathologically.…”

Section: Discussionmentioning

confidence: 99%

“…The spread of COVID-19 infection increased the number of patients who underwent pulmonary resection for lung cancer after COVID-19 infection [ 1 – 4 ]. It is unclear how previous infection with COVID-19 affects perioperative complications and acute exacerbation of interstitial pneumonia after surgery in patients with interstitial pneumonia.…”

Section: Introductionmentioning

confidence: 99%

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Lung cancer surgery after COVID-19 infection in a patient with severe interstitial pneumonia and restrictive ventilatory impairment

Komatsu¹,

Izumi²,

Tsukioka³

et al. 2022

surg case rep

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Background The spread of COVID-19 infection increased the number of patients who underwent pulmonary resection for lung cancer after COVID-19 infection. It is unclear how previous infection with COVID-19 affects perioperative complications and acute exacerbation of interstitial pneumonia after surgery in patients with interstitial pneumonia. Case presentation An 80-year-old man was referred to our hospital because of a tumor in his left lung. Chest computed tomography showed a 28-mm nodule in the lower lobe of the left lung and usual interstitial pneumonia in bilateral lungs. Bronchoscopic examination was performed, which diagnosed squamous cell carcinoma. Pulmonary function testing revealed restrictive ventilatory impairment, and we planned to perform basal segmentectomy of the left lung. However, before the planned surgery, the patient contracted symptomatic COVID-19. Chest computed tomography revealed ground-glass opacities owing to COVID-19. The patient was admitted for surgery 7 weeks after COVID-19 infection. Preoperatively, pulmonary function testing was repeated, which revealed decreased % vital capacity (%VC) and % diffusing capacity for carbon monoxide (%DLco). The 6-min walk test indicated a distance of 500 m, and the percutaneous oxygen saturation at the end of the test was 94%. Basal segmentectomy of the left lung was performed by video-assisted thoracoscopic surgery. The patient’s postoperative course was favorable, and he was discharged without the need for oxygen inhalational therapy 12 days after the surgery. Pathological examination of the resected specimen revealed usual interstitial pneumonia in the non-cancerous areas of the lung. Additionally, the infiltration of immature fibroblasts in the alveoli and perivascular infiltration of inflammatory cells were observed, which were consistent with fibrotic change after inflammation owing to COVID-19. Three months after the surgery, the patient was alive without recurrence or acute exacerbation of the interstitial pneumonia. Pulmonary function testing 6 weeks after surgery revealed decreased %VC and %DLco. Testing 12 weeks after surgery revealed persistently decreased %VC and improved %DLco (Table 1).Table 1 Pulmonary function test results before and after COVID-19 infection and 6 and 12 weeks after surgery VC (ml) %VC (%) %DLco (%) Before COVID-19 infection 2070 71.9 74.9 7 weeks after COVID-19 infection 1700 59.6 51.9 6 weeks after surgery 1500 52.6 53.1 12 weeks after surgery 1510 53.0 61.7 %VC % vital capacity, %DLco % diffusing capacity for carbon monoxide Conclusion We successfully performed basal segmentectomy of the left lung for lung cancer 7 weeks after COVID-19 infection in a patient with severe interstitial pneumonia and restrictive ventilatory impairment.

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Section: Discussionsupporting

confidence: 42%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Lung cancer surgery after COVID-19 infection in a patient with severe interstitial pneumonia and restrictive ventilatory impairment

Komatsu¹,

Izumi²,

Tsukioka³

et al. 2022

surg case rep

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show abstract

“…We suspect that, as in the case of other serious respiratory diseases, COVID-19 and the lung damage caused by the disease may affect the early outcomes of lung cancer surgery, including postoperative complications. To our knowledge, only case reports and short case-series were published on the subject up to date [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Outcomes of lung cancer surgery in patients with COVID-19 history: a single center cohort study

Gabryel

Zielińska

Skrzypczak

et al. 2022

Gen Thorac Cardiovasc Surg

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Objectives Coronavirus disease 2019 (COVID-19) can irreversibly damage the lungs and could possibly increase the risk of surgical treatment of lung cancer. The study aimed to assess the relationship between preoperative COVID-19 and complications and early outcomes of lung cancer surgery. Methods This single-center cohort study included 444 patients who underwent lobectomy or segmentectomy for primary lung cancer from January 1, 2019 to December 31, 2021. The exclusion criteria were pneumonectomy, extended resection, and wedge resection. The groups of patients with (n = 72) and without (n = 372) the history of COVID-19 prior to surgery were compared. The groups were similar in terms of distribution of baseline, surgical and histopathological characteristics. The primary endpoint was the incidence of postoperative complications. Secondary endpoints were outcomes at discharge and at 90 days. Results The incidence of postoperative complications did not differ between the groups of patients with and without COVID-19 history (30.6% vs 29.3%, p = 0.831). Outcomes at discharge and at 90 days after surgery did not differ between the groups. Among the patients with and without prior COVID-19, 97.2 and 99.5% were alive at discharge (p = 0.125), and 97.2% and 98.1% ninety days after surgery (p = 0.644), respectively. Patients with COVID-19 history more often required re-drainage (6.9% v 2.2%, p = 0.044) and reoperation (5.6 v 1.3%, p = 0.042). Conclusions COVID-19 history is not related to the general incidence of complications, outcomes at discharge from the hospital, and at 90-days after surgery.

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Bilobectomy for synchronous multiple lung cancer after COVID-19 pneumonia: a case report

Ishibashi¹,

Wada²,

Kamata³

et al. 2022

AME Case Rep

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Elective lung resection after treatment for COVID-19 pneumonia

Cited by 9 publications

References 3 publications

Lung cancer surgery after COVID-19 infection in a patient with severe interstitial pneumonia and restrictive ventilatory impairment

Lung cancer surgery after COVID-19 infection in a patient with severe interstitial pneumonia and restrictive ventilatory impairment

Outcomes of lung cancer surgery in patients with COVID-19 history: a single center cohort study

Bilobectomy for synchronous multiple lung cancer after COVID-19 pneumonia: a case report

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