Elective egg freezing without medical indications

Alteri, Alessandra; Pisaturo, Valerio; Nogueira, Daniela; D’Angelo, Arianna

doi:10.1111/aogs.13573

Cited by 43 publications

(33 citation statements)

References 51 publications

(121 reference statements)

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“…The cost of freezing eggs is significant, with recurring annual storage costs, and it is a clear deterrent to women who are considering OFNMR. Ikhena‐Abel et al illustrated that financial reimbursement, as already offered by some companies, 54 would promote consideration of OFNMR among some women in the general public and was not viewed as coercive 19 . Companies such as Apple, Facebook, and Google offer subsidized freezing for some staff.…”

Section: Discussionmentioning

confidence: 99%

Exploring women’s attitudes, knowledge, and intentions to use oocyte freezing for non‐medical reasons: A systematic review

Platts

Trigg

Bracewell‐Milnes

et al. 2020

Acta Obstet Gynecol Scand

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Introduction Women are postponing childbearing and preventing age‐related fertility decline with oocyte freezing for non‐medical reasons (OFNMR). The objective of this systematic evaluation was to gain an understanding of women's attitudes and knowledge of, and intentions to use OFNMR among users of OFNMR and the general public. Material and methods A systematic search of MEDLINE, EMBASE, and PyschINFO databases was undertaken, for studies that examined the psychosocial attitudes among women toward OFNMR. The search was limited to English language and no time restriction was set for publications. Extracted data were analyzed using thematic analysis and the study was performed according to PRISMA guidelines with prospective PROSPERO registration (CRD4201912578). Results Overall, 35 studies met the inclusion criteria. Studies were broadly categorized into studies investigating users or potential users of OFNMR, and studies examining the views of members of the general public. Users of OFNMR have good knowledge of age‐related fertility decline and awareness of the OFNMR procedure. Lack of partner was identified as the most common motivating factor to undertake OFNMR, with cost as a predominant concern. Knowledge among the general public of OFNMR is highly variable. Underestimation of age‐related fertility decline is common among the general public. Intentions of women to use OFNMR also varied drastically between studies. Conclusions Women are predominantly motivated to freeze eggs by the lack of a suitable partner, but cost is a significant barrier. Increasing the number of women pursuing OFNMR at an earlier stage may positively impact upon the risk of future involuntary childlessness. Better information should be made available to both women and men about their fertility and options to inform their reproductive decision‐making.

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Section: Discussionmentioning

confidence: 99%

Exploring women’s attitudes, knowledge, and intentions to use oocyte freezing for non‐medical reasons: A systematic review

Platts

Trigg

Bracewell‐Milnes

et al. 2020

Acta Obstet Gynecol Scand

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“…Due to postponement of childbearing, low ovarian reserve has become an important matter in female infertility (Ubaldi et al, 2019). The growing number of fertility preservation cycles performed for social reasons in IVF clinics in developed countries signals the success of the efforts made to communicate the effects of female age on oocyte quality and ovarian reserve (Alteri et al, 2019). However, a significant portion of the population still cannot afford ART procedures.…”

Section: Topic Frequencymentioning

confidence: 99%

Research priorities in infertility and assisted reproductive technology treatments - a James Lind Alliance priority setting partnership with brazilian patients

Lorenzon-Ojea

García²,

Silva

et al. 2020

JBRA Assisted Reproduction

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Objective: To identify the main research interests of Brazilian patients in the field of infertility and assisted reproductive technology (ART) treatments. Methods: This prospective multicenter cross-sectional study was carried out in Brazil. Patients attending five fertility centers from the Huntington Group between October and December 2018 were invited to join the study, which consisted of answering an anonymous survey online. Two hundred and twenty-seven patients signed the informed consent form and were emailed the survey link. The survey was designed based on the James Lind Alliance Priority Setting Partnership protocol. In the area of infertility, patients were probed on issues such as somatic and psychological effects of treatment, prevention, assisted reproductive technology (medications and procedures), success rates, risks, and emotional aspects. Results: The response rate (RR) was 47.58% (108 patients; 88 women-RR 51.46% and 20 men-RR 35.71%). Patient mean age was 36.5 years (SD 4.6). The top ten research priorities listed were 1) short-and long-term side effects of treatment; 2) how to cope with infertility; 3) risks associated with ART; 4) success rates in ART; 5) impact of diet on ART and fertility; 6) healthy habits; 7) alternative therapies; 8) impact of exercise on fertility and ART success; 9) oocyte quality and ovarian reserve; and 10) genetic or inherited causes of infertility. Conclusion: To better cater to the needs of patients and develop patient-centered care in the field of infertility and ART treatment, clinicians, healthcare providers, and the scientific community must identify patient concerns and priorities and make efforts to address them.

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“…The chance of having the desired outcomes such as high oocyte survival and live birth rates depend on womens’ age,13 the number of retrieved mature oocytes14 and the number of frozen eggs 13. Previous studies’ report lack agreement regarding the optimal timing of oocyte cryopreservation 9 14 15. One study showed the live birth rate was higher among women aged ≤35 years compared the older women (>35 years) 14.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of social egg freezing: protocol for systematic review and meta-analyses

Wang

Asefa

Kaan³

et al. 2019

BMJ Open

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IntroductionSocial egg freezing is storing egg for the purpose of preserving fertility and delayed childbearing. Currently, little is known about the utilisation and effectiveness of this approach. This review aims to determine (1) the proportion of women who used their stored eggs, and (2) the egg survival rate through vitrification, and the clinical pregnancy rate and live birth rate per 100 women partaking in the procedure, and among women who stored their eggs for medical reasons.Methods and analysesThis systematic review will be done according to the items listed in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. PubMed, Embase, Scopus, The Cumulative Index to Nursing and Allied Health Literature (CINAHL) and the Cochrane Library and Health Technology Assessment databases will be searched to identify eligible studies published since 2012. Two reviewers will independently appraise the eligibility and quality of the studies based on preset checklists and extract the data using a data extraction template. Outcomes of interest are proportion of women who used their stored eggs, egg survival rate, pregnancy rate and live birth rates. We will determine the presence heterogeneity among studies using the Cochrane’s Q test. The percentage of total variation across studies, which is due to statistical heterogeneity, will be calculated using the I2 statistics. Outcomes of interest will be pooled together using metaprop programme STATA V.14.Ethics and disseminationFor this review, ethical committee approval is not required. We will use publically available data from previously published studies. The final report of the review will be disseminated through publication on national or international journal, and it will be presented on different scientific conferences.PROSPERO registration numberCRD42018114254.

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Elective egg freezing without medical indications

Cited by 43 publications

References 51 publications

Exploring women’s attitudes, knowledge, and intentions to use oocyte freezing for non‐medical reasons: A systematic review

Exploring women’s attitudes, knowledge, and intentions to use oocyte freezing for non‐medical reasons: A systematic review

Research priorities in infertility and assisted reproductive technology treatments - a James Lind Alliance priority setting partnership with brazilian patients

Effectiveness of social egg freezing: protocol for systematic review and meta-analyses

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