Elastogenesis in Focus: Navigating Elastic Fibers Synthesis for Advanced Dermal Biomaterial Formulation
Roman Krymchenko,
Gizem Coşar Kutluoğlu,
Noor van Hout
et al.
Abstract:Elastin, a fibrous extracellular matrix (ECM) protein, is the main component of elastic fibers that are involved in tissues’ elasticity and resilience, enabling them to undergo reversible extensibility and to endure repetitive mechanical stress. After wounding, it is challenging to regenerate elastic fibers and biomaterials developed thus far have struggled to induce its biosynthesis. This review provides a comprehensive summary of elastic fibers synthesis at the cellular level and its implications for biomate… Show more
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