Elastic properties of osteon and trabecular bone measured by nanoindentation

Rho, Jae-Young; Tsui, Ting Y.; Pharr, G. M.

doi:10.1016/s0021-9290(98)80045-6

Cited by 10 publications

(7 citation statements)

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“…Ascenzi and Bonucci (1967) calculated a Young's modulus of 10.7 GPa for a single osteon. Rho et al (1998) calculated a modulus of 21.7 GPa but the value might have been overestimated because the bone specimens used were dehydrated, which can lead to an increase in stiffness (Elices 2000). Therefore the simulations also include cases in which a Young's modulus of 12 GPa is used for the pedicle.…”

Section: Materials Propertiesmentioning

confidence: 99%

On the Coupling Between the Incus and the Stapes in the Cat

Funnell

Siah

McKee

et al. 2005

JARO

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The connection between the long process and the lenticular process of the incus is extremely fine, so much so that some authors have treated the lenticular process as a separate bone. We review descriptions of the lenticular process that have appeared in the literature, and present some new histological observations. We discuss the dimensions and composition of the lenticular process and of the incudostapedial joint, and present estimates of the material properties for the bone, cartilage, and ligament of which they are composed. We present a preliminary finiteelement model which includes the lenticular plate, the bony pedicle connecting the lenticular plate to the long process, the head of the stapes, and the incudostapedial joint. The model has a much simplified geometry. We present simulation results for ranges of values for the material properties. We then present simulation results for this model when it is incorporated into an overall model of the middle ear of the cat. For the geometries and material properties used here, the bony pedicle is found to contribute significant flexibility to the coupling between the incus and the stapes.

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Section: Materials Propertiesmentioning

confidence: 99%

On the Coupling Between the Incus and the Stapes in the Cat

Funnell

Siah

McKee

et al. 2005

JARO

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“…The application areas include microelectronics, optoelectronics, coatings for low-emission window glasses, and tribological coatings [22][23][24][25][26][27][28]. Presently, there is also a growing interest in probing biological materials [29][30][31][32][33][34][35] and food products [36,37]. Instrumented indentation measurements have also been used in the study of the deformation and fracture of rocks for a better understanding of rock mechanics related to geological evolution of the planets [38,39].…”

Section: Introductionmentioning

confidence: 99%

Scaling, dimensional analysis, and indentation measurements

Cheng

2004

Materials Science and Engineering: R: Reports

939

512

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We provide an overview of the basic concepts of scaling and dimensional analysis, followed by a review of some of the recent work on applying these concepts to modeling instrumented indentation measurements. Specifically, we examine conical and pyramidal indentation in elastic-plastic solids with power-law workhardening, in power-law creep solids, and in linear viscoelastic materials. We show that the scaling approach to indentation modeling provides new insights into several basic questions in instrumented indentation, including, what information is contained in the indentation load-displacement curves? How does hardness depend on the mechanical properties and indenter geometry? What are the factors determining piling-up and sinking-in of surface profiles around indents? Can stress-strain relationships be obtained from indentation load-displacement curves? How to measure time dependent mechanical properties from indentation? How to detect or confirm indentation size effects? The scaling approach also helps organize knowledge and provides a framework for bridging micro-and macroscales. We hope that this review will accomplish two purposes: (1) introducing the basic concepts of scaling and dimensional analysis to materials scientists and engineers, and (2) providing a better understanding of instrumented indentation measurements. # 2004 Published by Elsevier B.V.

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“…Atomic force microscopy has been used extensively to measure stiffness of substrates for cell culture [43] and the stiffness properties of individual cells [44]. Studies pertaining to whole native tissues are however more rare: they concern mainly bones [45], cartilages [46] or arteries [47,48] and usually feature only topographical data; elastic modulus properties have only been studied in a few cases [47,49]. The topography of live embryonic tissue has recently been studied with the AFM [50].…”

Section: Atomic Force Microscopymentioning

confidence: 99%