Elastic fibers in the anterior abdominal wall

Fachinelli, Aldo; Trindade, Manoel Roberto Maciel; Fachinelli, F. A.

doi:10.1007/s10029-011-0804-2

Cited by 22 publications

(10 citation statements)

References 27 publications

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“…Elastin gives tissues in the human body elasticity. Fachinelli et al [15] reported that a significant higher amount of elastin is found in the abdominal wall in patients with ventral hernias. These findings suggest that not only anatomical diversity but also microscopic and histological factors plays a role in the acquirement of epigastric hernias.…”

Section: Microscopic Studiesmentioning

confidence: 98%

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Pathogenesis of the epigastric hernia

Ponten

Somers

Nienhuijs

2012

Hernia

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Section: Microscopic Studiesmentioning

confidence: 98%

“…Recent microscopic anatomical studies show that not only the macroscopic anatomy of the linea alba is important in epigastric hernia pathology, but that the microscopic aspects should also be considered [14,15]. Degeneration of collagen is associated with the requirement of several ventral hernias [14,16].…”

Section: Microscopic Studiesmentioning

confidence: 99%

Pathogenesis of the epigastric hernia

Ponten

Somers

Nienhuijs

2012

Hernia

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“…In a combination of epigastric, incisional, and umbilical hernias, the amount of elastin was significantly increased although the structure of the elastic fibers was altered, demonstrating a fragmented, thickened shape in patients with ventral hernia. 26 …”

Section: Evidence For Collagenopathies In Herniasmentioning

confidence: 99%

Collagenopathies—Implications for Abdominal Wall Reconstruction: A Systematic Review

Harrison

Sanniec

Janis

2016

Plastic and Reconstructive Surgery - Global Open

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Background:The etiology of hernia formation is strongly debated and includes mechanical strain, prior surgical intervention, abnormal embryologic development, and increased intraabdominal pressure. Although the most common inciting cause in ventral hernias is previous abdominal surgery, many other factors contribute. We explore this etiology through an examination of the current literature and existing evidence on patients with collagen vascular diseases, such as Ehlers–Danlos syndrome.Methods:A systematic review of the published literature was performed of all available Spanish and English language PubMed and Cochrane articles containing the key words “collagenopathies,” “collagenopathy,” “Ehlers-Danlos,” “ventral hernia,” and “hernia.”Results:Three hundred fifty-two articles were identified in the preliminary search. After review, 61 articles were included in the final review.Conclusions:Multiple authors suggest a qualitative or quantitative defect in collagen formation as a common factor in hernia formation. High-level clinical data clearly linking collagenopathies and hernia formation are lacking. However, a trend in pathologic studies suggests a link between abnormal collagen production and/or processing that is likely associated with hernia development.

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“…There has been research to suggest that patients with hernias have less type I collagen and more elastin in the linea alba than patients without hernias. 22,23 This type of connective tissue disorder is not otherwise clinically apparent, but likely predisposes certain individuals to developing a hernia. Of course, more obvious sources of trauma, such as blunt force from a motor vehicle collision or heavy blow to the abdomen, can cause a hernia as well.…”

Section: Etiologymentioning

confidence: 99%