Abstract:Single-administration vaccine delivery systems are intended to improve the efficiency and efficacy of immunisation programs in both human and veterinary medicine. In this work, an osmotically triggered delayed delivery device was developed that was able to release a payload after a delay of approximately 21 days, in a consistent and reproducible manner. The device was constructed out of a flexible poly(ε-caprolactone) photo-cured network fabricated into a hollow tubular shape, which expelled approximately 10% … Show more
“…Concerning the vaccine field, Melchels et al developed elastic bioresorbable polymeric capsules for the osmosis-driven delayed burst delivery of vaccines. This device osmotically delayed delivery and was able to release a payload after a delay of approximately 21 days in a consistent and reproducible manner [15].…”
“…Concerning the vaccine field, Melchels et al developed elastic bioresorbable polymeric capsules for the osmosis-driven delayed burst delivery of vaccines. This device osmotically delayed delivery and was able to release a payload after a delay of approximately 21 days in a consistent and reproducible manner [15].…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.