The study of the value creation system in the strategic management of costs associated with diseases shows the need to focus the analysis on the activities that make it up, since they detail all the interrelated actions to achieve efficiency in their treatment, particularly in cervical cancer. The design of its value chain is important in the economic context in which it is created and the agents involved in its achievement, since the user, the provider and the financer of health care have different health, economic and political interests. Quantifying its economic impact on society is relevant for its economic evaluation, reducing uncertainty and optimizing the design of public policies. There are theoretical and methodological weaknesses in the methods for estimating their indirect costs, market imperfections and the postulates of economic theory as their main foundations. The objective of the article is to design the value chain of the disease and the calculation of its costs, which will be specified by highlighting which activities will be considered as contributing value to its treatments and which others will be considered as supporting activities for the beneficiary of its treatments, who will be the patient.