El peso de la comorbilidad del paciente se correlaciona con la gravedad de la disfunción eréctil

Garcı́a-Cruz, E.; Carrión, Albert; Ajami, Tarek; Álvarez, Marta Neira; Correas, M.; García, B.; Garcia, Juliana; González, Carlos; Portillo, J.A.; Romero-Otero, Javier; Simon, Chantal; Torremadé, J.; Vigués, F.; Alcaraz, Antonio

doi:10.1016/j.acuro.2017.03.011

Cited by 4 publications

(2 citation statements)

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“…However, an average QoL did not display a neutral impact on the odds of ED, indicating that any perceived QoL poorer than “good” may contribute to predict the presence of ED. As observed previously, the number of comorbidities also arose as an influencing factor for ED [27], albeit significance was found only for 3 or more comorbidities. Finally, due to the remarkable percentage of patients experiencing other sex-related problems in addition to ED, we included the most frequent causes of dissatisfaction in the model.…”

Section: Discussionmentioning

confidence: 66%

The Brief Sexual Symptom Checklist as a Screening Tool for Sex-Related Problems in the Primary Care Setting: Focus on Erectile Dysfunction

et al. 2018

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Purpose: To assess the performance of the Brief Sexual Symptom Checklist for men (BSSC-M) questionnaire in General Practitioner’s (GP) consults in Spain. Methods: Multicenter, cross-sectional study conducted in Spain among men ≥50 years, visiting a GP for any reason, and being able to answer self-administered questionnaires. Patients receiving medicines for erectile dysfunction (ED) and those with poor functional status were excluded. Sexual satisfaction was assessed by the BSSC-M, ED by the Sexual Health Inventory for Men (SHIM), and quality of life (QoL) using a 5-point Likert scale. Results: In all, 770 men met all the selection criteria and 556 patients (72.2%) reported sexually related problems, ED being the most frequent (n = 427; 55.5%). The SHIM score decreased progressively with the number of causes of sexual dissatisfaction. Prevalence of ED (SHIM ≤21) was greater in patients who referred problems with erection in the BSSC-M questionnaire (76 vs. 14%; p < 0.001). Multivariate analysis for ED prediction revealed that sexual dissatisfaction, QoL (average or low/very low), and the presence of 3 or more comorbidities significantly influenced the chances of having ED. Conclusions: Our results encourage the use of the BSSC-M for identifying suspicion of ED and other sexual problems in patients > 50 who visit their GP for a routine follow-up.

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Section: Discussionmentioning

confidence: 66%

The Brief Sexual Symptom Checklist as a Screening Tool for Sex-Related Problems in the Primary Care Setting: Focus on Erectile Dysfunction

et al. 2018

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“…Several studies evaluating the performance of CCI in subjects with ED are available in the literature. [23]. All these studies concluded CCI to be a reliable tool to assess male sexual health.…”

Section: Discussionmentioning

confidence: 98%

Prevalence of Erectile Dysfunction According to Chronic Comorbid Health Conditions: a Cross-sectional Study.

Lisco

Bartolomeo

Ramunni

et al. 2021

Preprint

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Introduction. The prevalence of erectile dysfunction (ED) increases along with the burden of chronic diseases. This retrospective study aimed to assess the prevalence and severity of ED according to the levels of chronic comorbidities.Material and Methods. Two hundred twenty-two outpatients referred to the Outpatients Clinic of Endocrinology and Metabolic Disease of Conversano Hospital (Italy) with ED complaints from January 2018 to December 2019 were retrospectively eligible for this cross-sectional study. The ED severity and comorbidities burden were assessed by the 5-item International Index of Erectile Function questionnaire (IIEF-5) and Charlson comorbidity index (CCI). A modified index (mCCI) was developed to integrate other common risk factors for ED and was compared to the original tool. The primary outcome was to assess the prevalence of ED according to the severity of CCI. The secondary outcomes included the correlation between 1) IIEF-5 and total testosterone (TT); 2) CCI and TT; 3) IIEF-5 and CCI. Finally, the performance of the CCI and mCCI were compared.Results. The overall prevalence of ED increased along with the CCI score: 45% (5 on 11) for CCI=0; 95% (19 on 20) for CCI=1; 91% (29 on 32) for CCI=2; 99% (158 on 160) for CCI≥3 (p<.0001) Moreover, IIEF-5 score was directly correlated with TT levels (r=0.67; p<.0001). CCI correlated with both TT levels and IIEF-5 score (r=-0.34 and -0.44; p<.0001, respectively). Finally, a lower IIEF-5 score was significantly and independently associated with higher age and CCI as well as lower TT and SHBG. Compared to the CCI, an equal performance was also found with the mCCI.Discussion. Our results showed that CCI and mCCI are reliable tools to assess the presence and severity of ED among outpatients referred to the endocrine center. However, some limitations should be considered, including the number of participants, which appeared underpowered; the single-center experience; possible underestimation of CCI referred to a diagnostic delay of included comorbidities; arbitrary assignment of burden-points to hypertension dyslipidemia and cigarette smoking.Conclusion. The present study found that CCI, a validated tool to assess the burden of comorbidities, correlates with both the prevalence and severity of ED. This confirms that ED is a reliable proxy of overall male health, but further studies are needed to confirm this potential application.

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Are Radial Pressure Waves Effective for the Treatment of Moderate or Mild to Moderate Erectile Dysfunction? A Randomized Sham Therapy Controlled Clinical Trial

Sandoval-Salinas

Saffon

Martínez

et al. 2022

The Journal of Sexual Medicine

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Introduction Radial wave therapy is commercialized as an option for the management of erectile dysfunction. However, the mechanism of action of the radial waves differs substantially from shock waves, so the evidence gathered for shock wave therapy cannot be extrapolated, and there are very few clinical trials with the radial wave. Aim To assess the efficacy and safety of radial wave therapy compared with sham therapy for the treatment of moderate and mild to moderate erectile dysfunction. Methods A randomized, double-blind, sham-controlled clinical trial was realized. Eighty patients with moderate erectile dysfunction, without sickle cell anemia, anticoagulation treatment, comorbidities, or conditions associated with secondary erectile dysfunction were included. The efficacy and safety were assessed at 6 and 10 weeks after randomization. Patients were randomized 1:1 to 1 of 2 arms: (i) 6 weekly sessions of radial wave therapy (RW group) or (ii) 6 weekly sessions of sham therapy (control group). All patients received sildenafil 25 mg. Outcome The primary outcome was the mean change in the International Index of Erectile Function - Erectile Function (IIEF-EF) domain score at 6 weeks after randomization. Results Eighty men were randomized. The average baseline IIEF-EF score was 16.3 (Standard Deviation - SD 3.2), and the median baseline Erection Hardness Score (EHS) was 3 (IQR 1). At 6 weeks after randomization, the mean change in the IIEF-EF score was 3.4 (95% confidence interval [CI] 1.5-5.2) in the RW group and 4.2 (95% CI 2.5-5.9) in the control group. No differences were observed between groups (P value =.742). No change was observed in the median EHS score in the evaluations. No serious adverse events occurred in 2 (5%) patients after radial wave therapy, and in 1 (2.5%) patient after sham therapy. Clinical Implications Knowledge of the effectiveness of radial waves protocols used for the treatment of moderate erectile dysfunction, helps doctors and patients in making decisions about the use of this therapy. Strengths & Limitations One strength is conducting the study with high methodological standards to minimize risk biases. Our results are limited to the evaluation of 1 specific protocol in moderate and mild to moderate erectile dysfunction. Conclusions No difference was found in this study between men with moderate and mild to moderate erectile dysfunction treated with radial waves and men treated with placebo sham therapy. Studies with different protocols of radial waves are necessary.

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El peso de la comorbilidad del paciente se correlaciona con la gravedad de la disfunción eréctil

Cited by 4 publications

References 35 publications

The Brief Sexual Symptom Checklist as a Screening Tool for Sex-Related Problems in the Primary Care Setting: Focus on Erectile Dysfunction

The Brief Sexual Symptom Checklist as a Screening Tool for Sex-Related Problems in the Primary Care Setting: Focus on Erectile Dysfunction

Prevalence of Erectile Dysfunction According to Chronic Comorbid Health Conditions: a Cross-sectional Study.

Are Radial Pressure Waves Effective for the Treatment of Moderate or Mild to Moderate Erectile Dysfunction? A Randomized Sham Therapy Controlled Clinical Trial

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