Abstract:Alkylphenols are known endocrine-disrupting chemicals present in water bodies as contaminants, affecting aquatic life adversely. In this study, post vitellogenic follicles of the catfish Heteropneustes fossilis were in vitro exposed to 4-nonylphenol (4-NP) at concentrations of 0.1, 0.5, 1, 10, 100 and 200 ng/mL for 12 and 24 h. Germinal vesicle breakdown (GVBD), an indicator of final oocyte maturation (FOM), and the mortality of ovarian follicles were monitored. Levels of estradiol-17β (E2), testosterone (T), … Show more
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