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Abstract

ABSTRACT:Here, we evaluated the in vitro antileishmanial activities of Olea europaea linn. leave extract (OLE) on some Leishmania spp. OLE (0-160 g/mL) was considered against promastigote and intracellular amastigote forms of L. tropica (MHOM/IR/2002/Mash2) and L. major (MRHO/IR/75/ER) using MTT assay and in a macrophage model, respectively. The obtained findings demonstrated that OLE significantly ( <0.05) inhibited the growth rate of promastigote and amastigotes as a dose and time dependent response. To conclude, the current investigation exhibited effective antileishmanial activity of OLE.