Eisenmenger Syndrome in Pregnancy

Yuan, Shi‐Min

doi:10.5935/1678-9741.20160062

Cited by 26 publications

(42 citation statements)

References 33 publications

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“…Furthermore, the high peri−/postpartum risk due to hemodynamic stress and bleeding complications can lead to right HF [25,26]. In this scenario, premature birth and growth retardation are reported in successfully delivered children [27]. The same result was also detected in our study.…”

Section: Patient Characteristics and Outcomessupporting

confidence: 87%

Real-world in-hospital outcomes and potential predictors of heart failure in primigravid women with heart disease in Southwestern China

Wang

Feng

et al. 2020

BMC Pregnancy Childbirth

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Background: Little is known about the status of maternal, obstetric, and neonatal complications and the potential predictors of developing heart failure (HF) in mothers with underlying heart disease (HD) in Southwestern China. Methods: The eligible records from the YiduCloud database from December 1, 2010 to December 31, 2019 were screened. The maternal clinical characteristics and the in-hospital outcomes were collected and compared in primigravid women with and without HD. The HD subtypes analyzed included valvular HD (VHD), cardiomyopathy, adult congenital HD (ACHD), pulmonary hypertension (PH), and other cardiac conditions. Results: Among 45,067 primigravid women, 508 (1.1%) had HD, in which 207 (41%) had ACHD, 66 (13%) had VHD, 84 (17%) had cardiomyopathy, 7 (1%) had PH, and 144 (28%) had other cardiac diseases. The maternal cardiac events and the neonatal complications occurred in 28% and 23.3%, respectively, of women with HD and were predominant in the PH group. In multivariable regression, HF was associated with the New York Heart Association (NYHA) class ≥3 (OR = 15.9, 95% confidence interval [CI] = 2.5-99.7; P = 0.003), heart rate ≥ 100 bpm (OR = 3.8, 95% CI = 1.1-13.5; P = 0.036), ejection fraction ≤60% (OR = 6.4, 95% CI = 2.0-21.0; P = 0.002) and left ventricular enddiastolic diameter ≥ 50 mm (OR = 3.4, 95% CI = 1.1-11.2; P = 0.041) at the beginning of pregnancy. Conclusions: Maternal and neonatal complications are higher in primigravid women with HD particularly in the PH group compared with primigravid women without HD. Women with HD should be guided on the potential predictors for HF and closely monitored during pregnancy to reduce maternal and neonatal complications.

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Section: Patient Characteristics and Outcomessupporting

confidence: 87%

Real-world in-hospital outcomes and potential predictors of heart failure in primigravid women with heart disease in Southwestern China

Wang

Feng

et al. 2020

BMC Pregnancy Childbirth

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“…La disminución grave del gasto cardíaco unido a la resistencia vascular sistémica (RVS) tiene la potencialidad de aumentar la derivación de sangre de derecha a izquierda, con la posibilidad de inducir al colapso circulatorio y la insuficiencia cardíaca; lo que constituyó la injuria clínica que se manifestó en el paciente en cuestión. (12,13) La insuficiencia cardíaca produce una disminución del flujo sanguíneo hepático con la consecuente afectación del aporte de oxígeno, ocasionando la necrosis de los hepatocitos del área 3. (14) A su vez, la hipoxia estimula el incremento de la presión venosa capilar, el desarrollo de fibrosis y la hipertensión portal, los que junto a la disminución de la síntesis proteica y los factores de coagulación provocan un cuadro de ascitis y trastornos hemorrágicos.…”

Section: Discussionunclassified

Paciente con síndrome de Eisenmenger complicado por sangrado digestivo alto

Alcocer¹,

Chico

Zayas

2020

EUGENIO ESPEJO

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El Síndrome de Eisenmenger es un desorden multisistémico caracterizado por hipertensión pulmonar con inversión o bidireccionalidad del flujo a través de una comunicación intracardíaca o aortopulmonar. Se presenta el caso de un paciente masculino de 48 años de edad con antecedentes de Hipertensión Pulmonar e Insuficiencia Cardíaca en tratamiento, quien acude por cuadro de melenas, decaimiento e inestabilidad hemodinámica. Al examen físico se ausculta soplo sistólico ascendente en foco pulmonar, abdomen distendido con presencia de onda ascítica. En los exámenes complementarios; la radiografía convencional de tórax mostró aumento de la trama vascular pulmonar, además de encontrarse alteraciones electrocardiográficas. El paciente mostró una evolución desfavorable produciéndose falla cardíaca, que dio lugar al posterior fallecimiento debido a un paro cardiorrespiratorio.

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“…12. Pulmonary Artery Hypertension and Eisenmenger's Syndrome [46][47][48][49] Pulmonary artery hypertension (PAH) in CHDs can be due to large post-tricuspid shunts or complex cyanotic heart lesions with increased pulmonary blood flow. Unoperated, these conditions cause pulmonary vascular obstructive disease.…”

Section: Managementmentioning

confidence: 99%

Pregnancy in Congenital Heart Diseases

Bakhru

2018

Ind J Car Dis Wom

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Congenital heart diseases (CHDs) affect 0.8 to 1.5% of general population. With increase in awareness and medical services, more number of patients with CHDs have entered into adulthood. One of the peculiar physiologic changes in women is going through pregnancy. Misconceptions are common in women with CHD. This write-up is to provide some brief information about CHD patients going through pregnancy. General cardiovascular risk and individual disease-related risks are discussed.

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Eisenmenger Syndrome in Pregnancy

Cited by 26 publications

References 33 publications

Real-world in-hospital outcomes and potential predictors of heart failure in primigravid women with heart disease in Southwestern China

Real-world in-hospital outcomes and potential predictors of heart failure in primigravid women with heart disease in Southwestern China

Paciente con síndrome de Eisenmenger complicado por sangrado digestivo alto

Pregnancy in Congenital Heart Diseases

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