Einführung in die Chemische Physiologie

Lehnartz, Emil

doi:10.1007/978-3-642-86501-5

Cited by 30 publications

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“…In the literature on thermal behavior of acrylic cement, as discussed in the previous chapter, the threshold temperatures of collagen denaturation (56°C, Lehnartz ( 1959); 60°C, Viidik ( 1972); 70°C, Labitzke and Pa u lus ( 197 4)) is usually taken as a criterion. lt has been established, however, that collagen is more temperature-resistent than the protoplasm proteins (Lundskog, 1972).…”

Section: Threshold Levels Forthermal Bone Necrosismentioning

confidence: 99%

Some Fundamental Aspects of Human Joint Replacement: Analyses of Stresses and Heat Conduction in Bone-Prosthesis Structures

Huiskes

1980

Acta Orthopaedica Scandinavica

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Section: Threshold Levels Forthermal Bone Necrosismentioning

confidence: 99%

Some Fundamental Aspects of Human Joint Replacement: Analyses of Stresses and Heat Conduction in Bone-Prosthesis Structures

Huiskes

1980

Acta Orthopaedica Scandinavica

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“…The heat of polymerisation of cement may be an important factor in initial bone necrosis (Di Pisa, Sih and Berman 1976), and Lenhartz (1959) has cited the threshold temperature of collagen denaturation (56°C) as one criterion. Moritz and Henriques (1947) found a time-dependent threshold level for cell necrosis reporting that a temperature of 50°C for three minutes kills bone cells.…”

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Porosity Reduction in Bone Cement at the Cement-Stem Interface

Bishop

Ferguson

Tepic

1996

The Journal of Bone and Joint Surgery. British volume

126

137

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The fatigue failure of bone cement, leading to loosening of the stem, is likely to be one mode of failure of cemented total hip replacements. There is strong evidence that cracks in the cement are initiated at voids which act as stress risers, particularly at the cementstem interface. The preferential formation of voids at this site results from shrinkage during polymerisation and the initiation of this process at the warmer cementbone interface, which causes bone cement to shrink away from the stem. A reversal of the direction of polymerisation would shrink the cement on to the stem and reduce or eliminate the formation of voids at this interface. We have investigated this by implanting hip prostheses, at room temperature or preheated to 44°C, into human cadaver femora kept at 37°C. Two types of bone cement were either hand-mixed or vacuum-mixed before implantation. We found that the area of porosity at the cement-stem interface was dramatically reduced by preheating the stem and that the preheating temperature of 44°C determined by computer analysis of transient heat transfer was the minimum required to induce initial polymerisation at the cement-stem interface. Temperature measurements taken during these experiments in vitro showed that preheating of the stem caused a negligible increase in the temperature of the bone. Reduction of porosity at the cement-stem interface could significantly increase the life of hip arthroplasties.

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2009

Die Bierbrauerei

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Einführung in die Chemische Physiologie

Cited by 30 publications

References 0 publications

Some Fundamental Aspects of Human Joint Replacement: Analyses of Stresses and Heat Conduction in Bone-Prosthesis Structures

Some Fundamental Aspects of Human Joint Replacement: Analyses of Stresses and Heat Conduction in Bone-Prosthesis Structures

Porosity Reduction in Bone Cement at the Cement-Stem Interface

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