Einfluss von bildgestützter translatorischer Isozentrumskorrektur auf die Dosisverteilung bei 3-D-Konformationsbestrahlung der Prostata

Wertz, H.; Lohr, Frank; Dobler, Barbara; Mai, Sabine; Wenz, Frederik

doi:10.1007/s00066-007-1619-z

Cited by 20 publications

(2 citation statements)

References 31 publications

(33 reference statements)

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“…Furthermore it is essential while in the case of the 3DCRT at a correct setup of the patient always the whole PTV is inside of the field, in the case of IMRT between segments, which should complement one another there might result an overlap or gap due to intrafractional movements. Interfractional movements are no particular problem of IMRT and the treatment accuracy can be improved by image guidance [1,19,23,24,27].…”

Section: Discussionmentioning

confidence: 99%

IMRT of prostate cancer

Treutwein

Hipp²,

Kölbl³

et al. 2009

Strahlenther Onkol

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Background and Purpose: Intensity-modulated radiation therapy (IMRT) has shown its superiority to 3D conformal radiotherapy in the treatment of prostate cancer. Different optimisation algorithms are available: algorithms which first optimise the fluence followed by a sequencing (IM) and algorithms which involve the machine parameters directly in the optimisation process (DSS). The aim of this treatment planning study is to compare both of them regarding dose distribution and treatment time.Patients, Material and Methods: Ten consecutive patients with localized prostate cancer were enrolled for this planning study. The planning target volume (PTV) and the rectum volume, urinary bladder and femoral heads as organs at risk (OAR) were delineated. Average doses, the target dose homogeneity H, D 5 , D 95 , monitor units per fraction and the number of segments were evaluated. Results:While there is only a small difference in the mean doses at rectum and bladder, there is a significant advantage for the target dose homogeneity in the DSS-optimised plans compared to the IMoptimised ones. Differences in the monitor units (nearly 10% less for DSS) and the number of segments are also statistically significant and reduce the treatment time. Conclusion:Particularly with regard to the tumor control probability the better homogeneity of the DSS-optimised plans is more profitable. The shorter treatment time is an improvement regarding intrafractional organ motion. The DSS-optimiser results in a higher target dose homogeneity and, simultaneously, in a lower number of monitor units. Therefore it should be preferred for IMRT of prostate cancer.

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Section: Discussionmentioning

confidence: 99%

IMRT of prostate cancer

Treutwein

Hipp²,

Kölbl³

et al. 2009

Strahlenther Onkol

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“…Dieser nicht unerhebliche Aufwand [4,9] wird im Gegensatz zu den USA in Deutschland nur unzureichend vergütet. Während CT zur Bestrahlungsplanung und zweidimensionale Verifikationen zur Positionskontrolle schon länger integraler Teil des Bestrahlungsprozesses sind, eröffnet die Einfüh-rung volumenbasierter bildgestützter Radiotherapie (IGRT ["image-guided radiotherapy"]) weitere, neue Behandlungsmöglichkeiten [2,3,10,11,18,25]. Die reibungslose Integration all dieser Techniken und der damit verbundenen Informationen in den Behandlungsablauf einer radioonkologischen Klinik ist in Zukunft nur noch mit Hilfe eines elektronischen Datenmanagementsystems zu leisten.…”

Section: Introductionunclassified

Patientenbezogenes Bild- und Datenmanagement in der Radioonkologie

et al. 2009

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: Since the transition to a paper- and filmless environment in medicine and especially in radiation oncology is unavoidable, this review discusses these issues and suggests a possible hardware and organizational architecture of an RT department information system under control of a Hospital Information System (HIS), based on combined features of genuine RT Record and Verify (R&V) Systems, PACS, and Electronic Medical Records (EMR).

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