Eine neue, effiziente Synthese von [1,3-¹³C₂]-Malonsäre-diethylester

Synthesis of an Isotopically Isomeric Mixture of 1,4,6,8‐Tetramethyl[13C2]azulene and Its Thermal Reaction with Dimethyl Acetylenedicarboxylate

“…of LiAIH, (4.6 g, 0.114 mol) in Et,O (600 ml). Thereafter, the mixture was heated for 3 h at reflux and then hydrolyzed in the following manner (see [31] [32]): after cooling to O", the mixture was treated with H,O (4.6 ml), 15% NaOH (4.6 g). and again, H,O (13.8 ml).…”

“…Preliminary experiments with non-labelled CO, had shown that the best yields of (trimethylsily1)acetic acid were obtained at pH 4.5 and not at pH 6 [31].…”

Synthesis of α-germyl and α-silylcarboxylic acids and selected electrochemical oxidations

“…a-Silylacetic acids (R 3 SiCH 2 COOH) are widely used to synthesize a,b-unsaturated carboxylic acids and butyrolactons [1], as well as labeled diethyl malonate and a-silylthioesters for biological purposes [2,3]. Recently we have shown that they could also be useful precursors for the synthesis of 1,2-disilylethanes in good yields by their electrochemical oxidation [4,5].…”